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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDUFS1 All Species: 38.18
Human Site: S650 Identified Species: 64.62
UniProt: P28331 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28331 NP_004997.4 727 79468 S650 R N R L E E V S P N L V R Y D
Chimpanzee Pan troglodytes Q0MQG2 727 79504 S650 R N R L E E V S P N L V R Y D
Rhesus Macaque Macaca mulatta XP_001105760 724 79061 S647 R N R L E E V S P N L V R Y D
Dog Lupus familis XP_536039 727 79660 S650 R H R L E E V S P N L V R Y D
Cat Felis silvestris
Mouse Mus musculus Q91VD9 727 79730 S650 R N R L E E V S P N L V R Y D
Rat Rattus norvegicus Q66HF1 727 79394 S650 R N R L G E V S P N L V R Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006518 728 79558 S651 R K R L E E V S P N L V R Y D
Frog Xenopus laevis NP_001080308 727 79557 S650 R E R L Q E V S P N L V R Y D
Zebra Danio Brachydanio rerio NP_001007766 731 79415 S654 R R R L A E V S P N L V R Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94511 731 78612 A656 R N R L E D V A P H L T R L G
Honey Bee Apis mellifera NP_001165875 727 80351 I654 I R S R L E E I A P H L I R Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_801919 730 79428 L656 I D G V R Q R L A D V S P N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FGI6 748 81507 G675 L P Y N S I E G V R S R I K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P24918 744 81583 S654 R D R M V E I S P A L S S Y D
Conservation
Percent
Protein Identity: 100 99.4 96 97.8 N.A. 94.2 94.9 N.A. N.A. 86.6 85.2 80.7 N.A. 62.1 64.7 N.A. 71.5
Protein Similarity: 100 99.8 97.1 99.4 N.A. 97.8 97.8 N.A. N.A. 93.5 93.6 91.5 N.A. 76.8 78.2 N.A. 83.9
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. N.A. 93.3 86.6 86.6 N.A. 60 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 93.3 93.3 86.6 N.A. 80 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 52.9 N.A. 53.2
Protein Similarity: N.A. N.A. N.A. 68.1 N.A. 68.6
P-Site Identity: N.A. N.A. N.A. 0 N.A. 53.3
P-Site Similarity: N.A. N.A. N.A. 0 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 15 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 8 0 0 0 8 0 0 0 0 72 % D
% Glu: 0 8 0 0 50 79 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 0 0 8 0 0 0 0 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 8 8 0 0 0 0 % H
% Ile: 15 0 0 0 0 8 8 8 0 0 0 0 15 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 8 0 0 72 8 0 0 8 0 0 79 8 0 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 43 0 8 0 0 0 0 0 65 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 0 0 0 79 8 0 0 8 0 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 79 15 79 8 8 0 8 0 0 8 0 8 72 8 0 % R
% Ser: 0 0 8 0 8 0 0 72 0 0 8 15 8 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 8 8 0 72 0 8 0 8 65 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 72 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _