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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADH6 All Species: 3.64
Human Site: Y139 Identified Species: 10
UniProt: P28332 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28332 NP_000663.1 368 39089 Y139 T C K G K S I Y H F G N T S T
Chimpanzee Pan troglodytes Q5R1W2 375 39808 I138 F T C R G K P I H H F L G T S
Rhesus Macaque Macaca mulatta P28469 375 39894 I138 F T C R G K P I H H F L G V S
Dog Lupus familis XP_535667 375 39781 I138 F T C R G K P I Y H F L G I S
Cat Felis silvestris
Mouse Mus musculus Q64437 374 39819 Q138 T C K G K P V Q H F M N T S T
Rat Rattus norvegicus Q5XI95 376 39708 H139 T C K G K L V H Q Y I A L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518992 382 40552 Y146 T C R G R K I Y H F A G T S T
Chicken Gallus gallus P23991 376 39789 A138 R F T C K G K A I H H F V G T
Frog Xenopus laevis NP_001086427 376 39998 I139 F T C K G Q Q I F H F M G T S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.9 61.8 62.4 N.A. 59 64 N.A. 61.7 63.2 58.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 77 76.8 77.5 N.A. 75.1 80.3 N.A. 75.1 78.1 73.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 0 N.A. 73.3 33.3 N.A. 66.6 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 13.3 13.3 N.A. 80 60 N.A. 80 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 12 12 0 0 0 % A
% Cys: 0 45 45 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 45 12 0 0 0 0 0 0 12 34 45 12 0 0 0 % F
% Gly: 0 0 0 45 45 12 0 0 0 0 12 12 45 23 0 % G
% His: 0 0 0 0 0 0 0 12 56 56 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 23 45 12 0 12 0 0 12 0 % I
% Lys: 0 0 34 12 45 45 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 34 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % N
% Pro: 0 0 0 0 0 12 34 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 12 12 12 0 0 0 0 0 0 % Q
% Arg: 12 0 12 34 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 0 0 0 0 0 0 34 56 % S
% Thr: 45 45 12 0 0 0 0 0 0 0 0 0 34 23 45 % T
% Val: 0 0 0 0 0 0 23 0 0 0 0 0 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 23 12 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _