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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLD1 All Species: 43.03
Human Site: S914 Identified Species: 78.89
UniProt: P28340 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28340 NP_002682.2 1107 123631 S914 M R K R D P G S A P S L G D R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116065 1327 147636 S914 M R K R D P G S A P S L G D R
Dog Lupus familis XP_851285 1107 123714 S914 M R K R D P G S A P S L G D R
Cat Felis silvestris
Mouse Mus musculus P52431 1105 123765 S912 M R K R D P G S A P S L G D R
Rat Rattus norvegicus O54747 1103 123583 S910 M R K R D P G S A P N L G D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087694 1109 125430 S919 M R K R D P G S A P N L G D R
Zebra Danio Brachydanio rerio NP_001034899 1105 124931 S918 M R K R D A G S A P N L G D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54358 1092 124887 T900 M K K R D P G T A P K L G D R
Honey Bee Apis mellifera XP_623795 1105 126747 N913 M K K R D A G N A P K L G D R
Nematode Worm Caenorhab. elegans P90829 1081 120811 S884 M K K R D A G S A P R L G D R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307042 1081 121993 T895 M R K R D A A T A P N V G D R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVN7 1081 121718 T909 M R K R D A A T A P N V G D R
Baker's Yeast Sacchar. cerevisiae P15436 1097 124572 V916 R M K R R E G V G P N V G D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 80.6 94.1 N.A. 89.4 89.8 N.A. N.A. N.A. 70.9 69.7 N.A. 59.4 58.9 49.6 N.A.
Protein Similarity: 100 N.A. 81.5 96.4 N.A. 94.1 94.3 N.A. N.A. N.A. 84 83 N.A. 74.8 74.4 67.9 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. N.A. 93.3 86.6 N.A. 80 73.3 80 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 100 93.3 N.A. 93.3 86.6 86.6 N.A.
Percent
Protein Identity: 54.9 N.A. N.A. 50.8 47 N.A.
Protein Similarity: 71 N.A. N.A. 67.4 65.1 N.A.
P-Site Identity: 66.6 N.A. N.A. 66.6 46.6 N.A.
P-Site Similarity: 86.6 N.A. N.A. 86.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 39 16 0 93 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 93 0 0 0 0 0 0 0 0 100 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 85 0 8 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 24 100 0 0 0 0 0 0 0 16 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 % L
% Met: 93 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 47 0 0 0 0 % N
% Pro: 0 0 0 0 0 54 0 0 0 100 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 70 0 100 8 0 0 0 0 0 8 0 0 0 100 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 31 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 24 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _