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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLD1 All Species: 40.3
Human Site: Y147 Identified Species: 73.89
UniProt: P28340 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28340 NP_002682.2 1107 123631 Y147 H I H G F A P Y F Y T P A P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116065 1327 147636 Y147 H I H G F A P Y F Y T P A P P
Dog Lupus familis XP_851285 1107 123714 Y147 H I H G F A P Y F Y T P A P S
Cat Felis silvestris
Mouse Mus musculus P52431 1105 123765 Y145 H I Q G F A P Y F Y T P A P P
Rat Rattus norvegicus O54747 1103 123583 Y143 H I H G F A P Y F Y T P A P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087694 1109 125430 Y141 H I H G F A P Y F Y V P C H T
Zebra Danio Brachydanio rerio NP_001034899 1105 124931 Y140 H I H G F A P Y F Y V P A P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54358 1092 124887 Y127 H V H G F C P Y F Y I E A P S
Honey Bee Apis mellifera XP_623795 1105 126747 Y144 H V H G F S P Y L Y V I A P T
Nematode Worm Caenorhab. elegans P90829 1081 120811 Q115 H F Y F Q A P Q G F G V E H I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307042 1081 121993 Y130 L V H G F E P Y F Y V S C P P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVN7 1081 121718 Y144 F V H G F E P Y F Y I A C P P
Baker's Yeast Sacchar. cerevisiae P15436 1097 124572 Y159 N V T G F K N Y L Y V P A P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 80.6 94.1 N.A. 89.4 89.8 N.A. N.A. N.A. 70.9 69.7 N.A. 59.4 58.9 49.6 N.A.
Protein Similarity: 100 N.A. 81.5 96.4 N.A. 94.1 94.3 N.A. N.A. N.A. 84 83 N.A. 74.8 74.4 67.9 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 100 N.A. N.A. N.A. 73.3 86.6 N.A. 66.6 60 20 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 100 N.A. N.A. N.A. 73.3 86.6 N.A. 73.3 73.3 33.3 N.A.
Percent
Protein Identity: 54.9 N.A. N.A. 50.8 47 N.A.
Protein Similarity: 71 N.A. N.A. 67.4 65.1 N.A.
P-Site Identity: 60 N.A. N.A. 60 46.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 62 0 0 0 0 0 8 70 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 24 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 16 0 0 0 0 0 8 8 0 0 % E
% Phe: 8 8 0 8 93 0 0 0 77 8 0 0 0 0 0 % F
% Gly: 0 0 0 93 0 0 0 0 8 0 8 0 0 0 0 % G
% His: 77 0 77 0 0 0 0 0 0 0 0 0 0 16 0 % H
% Ile: 0 54 0 0 0 0 0 0 0 0 16 8 0 0 8 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 16 % N
% Pro: 0 0 0 0 0 0 93 0 0 0 0 62 0 85 47 % P
% Gln: 0 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 16 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 39 0 0 0 16 % T
% Val: 0 39 0 0 0 0 0 0 0 0 39 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 93 0 93 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _