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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSX1
All Species:
13.94
Human Site:
S105
Identified Species:
25.56
UniProt:
P28360
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28360
NP_002439.2
297
30940
S105
G
A
P
D
A
P
S
S
P
R
P
L
G
H
F
Chimpanzee
Pan troglodytes
A2T764
267
28880
S103
V
K
P
F
E
T
A
S
V
K
S
E
N
S
E
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
S105
G
A
P
D
A
P
S
S
P
R
P
L
G
H
F
Dog
Lupus familis
XP_545946
236
25066
E74
A
E
S
P
E
K
P
E
R
T
P
W
M
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
P13297
293
30828
S105
G
A
P
D
A
P
S
S
P
R
P
L
G
H
F
Rat
Rattus norvegicus
P52953
139
15820
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507596
304
31847
P110
A
S
D
G
P
A
A
P
L
P
L
N
T
H
F
Chicken
Gallus gallus
P50223
288
30499
F106
P
L
P
L
G
G
H
F
P
S
V
G
A
L
G
Frog
Xenopus laevis
Q04281
295
32320
S111
A
A
G
E
T
P
N
S
P
I
S
L
G
N
R
Zebra Danio
Brachydanio rerio
Q01704
226
25849
V64
F
M
L
Q
T
S
P
V
K
S
E
S
P
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15857
79
9464
Nematode Worm
Caenorhab. elegans
Q09604
225
25209
M63
G
A
Q
L
D
P
V
M
I
Y
F
A
Q
T
G
Sea Urchin
Strong. purpuratus
NP_999778
286
31115
S113
E
N
I
L
A
K
S
S
S
S
S
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.2
99.3
76.7
N.A.
92.5
38.7
N.A.
73.6
74.4
63.2
49.1
N.A.
N.A.
23.5
34
40.7
Protein Similarity:
100
66.6
99.3
77.7
N.A.
92.9
41.4
N.A.
77.6
78.4
72
56.9
N.A.
N.A.
25.2
43.7
51.5
P-Site Identity:
100
13.3
100
6.6
N.A.
100
0
N.A.
13.3
13.3
40
0
N.A.
N.A.
0
20
20
P-Site Similarity:
100
26.6
100
6.6
N.A.
100
0
N.A.
26.6
13.3
60
0
N.A.
N.A.
0
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
39
0
0
31
8
16
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
24
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
16
0
0
8
0
0
8
8
0
8
8
% E
% Phe:
8
0
0
8
0
0
0
8
0
0
8
0
0
0
31
% F
% Gly:
31
0
8
8
8
8
0
0
0
0
0
8
31
0
16
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
31
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
16
0
0
8
8
0
0
0
0
0
% K
% Leu:
0
8
8
24
0
0
0
0
8
0
8
31
0
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
8
8
8
8
% N
% Pro:
8
0
39
8
8
39
16
8
39
8
31
0
8
0
8
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
24
0
0
0
0
8
% R
% Ser:
0
8
8
0
0
8
31
47
8
24
24
16
8
16
8
% S
% Thr:
0
0
0
0
16
8
0
0
0
8
0
0
8
8
0
% T
% Val:
8
0
0
0
0
0
8
8
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _