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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSX1
All Species:
13.33
Human Site:
S130
Identified Species:
24.44
UniProt:
P28360
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28360
NP_002439.2
297
30940
S130
D
A
L
V
K
A
E
S
P
E
K
P
E
R
T
Chimpanzee
Pan troglodytes
A2T764
267
28880
P126
P
G
R
Y
S
P
P
P
R
H
M
S
P
T
T
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
S130
D
A
L
V
K
A
E
S
P
E
K
P
E
R
T
Dog
Lupus familis
XP_545946
236
25066
C97
R
R
L
S
P
P
A
C
T
L
R
K
H
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P13297
293
30828
S130
D
A
L
V
K
A
E
S
P
E
K
L
D
R
T
Rat
Rattus norvegicus
P52953
139
15820
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507596
304
31847
S135
D
A
L
V
K
P
E
S
P
E
K
S
E
C
G
Chicken
Gallus gallus
P50223
288
30499
S137
E
R
S
P
W
M
Q
S
P
R
F
S
P
P
P
Frog
Xenopus laevis
Q04281
295
32320
K134
L
P
E
E
T
L
L
K
P
E
S
P
E
R
S
Zebra Danio
Brachydanio rerio
Q01704
226
25849
R87
N
S
R
Y
S
Q
T
R
Q
E
S
P
C
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15857
79
9464
Nematode Worm
Caenorhab. elegans
Q09604
225
25209
A86
D
S
S
P
E
S
C
A
S
S
P
L
S
M
Q
Sea Urchin
Strong. purpuratus
NP_999778
286
31115
F142
Y
T
W
N
A
S
S
F
P
W
M
Q
A
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.2
99.3
76.7
N.A.
92.5
38.7
N.A.
73.6
74.4
63.2
49.1
N.A.
N.A.
23.5
34
40.7
Protein Similarity:
100
66.6
99.3
77.7
N.A.
92.9
41.4
N.A.
77.6
78.4
72
56.9
N.A.
N.A.
25.2
43.7
51.5
P-Site Identity:
100
6.6
100
13.3
N.A.
86.6
0
N.A.
73.3
13.3
33.3
13.3
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
6.6
100
26.6
N.A.
93.3
0
N.A.
73.3
26.6
40
26.6
N.A.
N.A.
0
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
8
24
8
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
8
8
0
% C
% Asp:
39
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
8
8
8
0
31
0
0
47
0
0
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
31
0
0
8
0
0
31
8
0
8
8
% K
% Leu:
8
0
39
0
0
8
8
0
0
8
0
16
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
16
0
0
8
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
16
8
24
8
8
54
0
8
31
16
16
8
% P
% Gln:
0
0
0
0
0
8
8
0
8
0
0
8
0
0
8
% Q
% Arg:
8
16
16
0
0
0
0
8
8
8
8
0
0
31
0
% R
% Ser:
0
16
16
8
16
16
8
39
8
8
16
24
8
0
8
% S
% Thr:
0
8
0
0
8
0
8
0
8
0
0
0
0
16
39
% T
% Val:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _