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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSX1 All Species: 22.73
Human Site: T171 Identified Species: 41.67
UniProt: P28360 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28360 NP_002439.2 297 30940 T171 K T N R K P R T P F T T A Q L
Chimpanzee Pan troglodytes A2T764 267 28880 L167 K F R Q K Q Y L S I A E R A E
Rhesus Macaque Macaca mulatta Q2VL87 297 30903 T171 K T N R K P R T P F T T A Q L
Dog Lupus familis XP_545946 236 25066 F138 S I A E R A E F S S S L S L T
Cat Felis silvestris
Mouse Mus musculus P13297 293 30828 T171 K T N R K P R T P F T T A Q L
Rat Rattus norvegicus P52953 139 15820 I41 R Q K Q Y L S I A E R A E F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507596 304 31847 T176 K T N R K P R T P F T T A Q L
Chicken Gallus gallus P50223 288 30499 R178 A Q L L A L E R K F R Q K Q Y
Frog Xenopus laevis Q04281 295 32320 T175 K T N R K P R T P F T T S Q L
Zebra Danio Brachydanio rerio Q01704 226 25849 A128 Q K Q Y L S I A E R A E F S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera P15857 79 9464
Nematode Worm Caenorhab. elegans Q09604 225 25209 K127 K C M L R K H K N N R K P R T
Sea Urchin Strong. purpuratus NP_999778 286 31115 T183 K T N R K P R T P F T T S Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.2 99.3 76.7 N.A. 92.5 38.7 N.A. 73.6 74.4 63.2 49.1 N.A. N.A. 23.5 34 40.7
Protein Similarity: 100 66.6 99.3 77.7 N.A. 92.9 41.4 N.A. 77.6 78.4 72 56.9 N.A. N.A. 25.2 43.7 51.5
P-Site Identity: 100 13.3 100 0 N.A. 100 0 N.A. 100 13.3 93.3 0 N.A. N.A. 0 6.6 93.3
P-Site Similarity: 100 20 100 20 N.A. 100 13.3 N.A. 100 13.3 100 6.6 N.A. N.A. 0 20 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 8 0 8 8 0 16 8 31 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 16 0 8 8 0 16 8 0 8 % E
% Phe: 0 8 0 0 0 0 0 8 0 54 0 0 8 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 8 0 8 0 0 0 0 0 % I
% Lys: 62 8 8 0 54 8 0 8 8 0 0 8 8 0 0 % K
% Leu: 0 0 8 16 8 16 0 8 0 0 0 8 0 8 47 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 47 0 0 0 0 0 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 47 0 0 47 0 0 0 8 0 0 % P
% Gln: 8 16 8 16 0 8 0 0 0 0 0 8 0 54 0 % Q
% Arg: 8 0 8 47 16 0 47 8 0 8 24 0 8 8 0 % R
% Ser: 8 0 0 0 0 8 8 0 16 8 8 0 24 8 16 % S
% Thr: 0 47 0 0 0 0 0 47 0 0 47 47 0 0 16 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 8 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _