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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSX1
All Species:
22.73
Human Site:
T206
Identified Species:
41.67
UniProt:
P28360
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28360
NP_002439.2
297
30940
T206
F
S
S
S
L
S
L
T
E
T
Q
V
K
I
W
Chimpanzee
Pan troglodytes
A2T764
267
28880
E202
A
K
A
K
R
L
Q
E
A
E
L
E
K
L
K
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
T206
F
S
S
S
L
S
L
T
E
T
Q
V
K
I
W
Dog
Lupus familis
XP_545946
236
25066
M173
A
E
L
E
K
L
K
M
A
A
K
P
M
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P13297
293
30828
T206
F
S
S
S
L
S
L
T
E
T
Q
V
K
I
W
Rat
Rattus norvegicus
P52953
139
15820
E76
A
K
R
L
Q
E
A
E
L
E
K
L
K
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507596
304
31847
T211
F
S
S
S
L
S
L
T
E
T
Q
V
K
I
W
Chicken
Gallus gallus
P50223
288
30499
R213
K
I
W
F
Q
N
R
R
A
K
A
K
R
L
Q
Frog
Xenopus laevis
Q04281
295
32320
T210
F
S
S
S
L
N
L
T
E
T
Q
V
K
I
W
Zebra Danio
Brachydanio rerio
Q01704
226
25849
L163
K
R
L
Q
E
A
E
L
E
K
L
K
L
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15857
79
9464
F16
N
R
K
P
R
T
P
F
T
T
Q
Q
L
L
S
Nematode Worm
Caenorhab. elegans
Q09604
225
25209
F162
S
I
A
E
R
A
E
F
S
A
S
L
Q
L
T
Sea Urchin
Strong. purpuratus
NP_999778
286
31115
T218
F
S
A
S
L
N
L
T
E
T
Q
V
K
I
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.2
99.3
76.7
N.A.
92.5
38.7
N.A.
73.6
74.4
63.2
49.1
N.A.
N.A.
23.5
34
40.7
Protein Similarity:
100
66.6
99.3
77.7
N.A.
92.9
41.4
N.A.
77.6
78.4
72
56.9
N.A.
N.A.
25.2
43.7
51.5
P-Site Identity:
100
6.6
100
0
N.A.
100
6.6
N.A.
100
0
93.3
6.6
N.A.
N.A.
13.3
0
86.6
P-Site Similarity:
100
20
100
13.3
N.A.
100
26.6
N.A.
100
20
100
13.3
N.A.
N.A.
26.6
33.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
24
0
0
16
8
0
24
16
8
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
16
8
8
16
16
54
16
0
8
0
0
0
% E
% Phe:
47
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
0
0
47
0
% I
% Lys:
16
16
8
8
8
0
8
0
0
16
16
16
62
0
8
% K
% Leu:
0
0
16
8
47
16
47
8
8
0
16
16
16
39
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% M
% Asn:
8
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
8
% P
% Gln:
0
0
0
8
16
0
8
0
0
0
54
8
8
0
8
% Q
% Arg:
0
16
8
0
24
0
8
8
0
0
0
0
8
0
0
% R
% Ser:
8
47
39
47
0
31
0
0
8
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
47
8
54
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
47
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _