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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
55.15
Human Site:
T185
Identified Species:
93.33
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
T185
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Chimpanzee
Pan troglodytes
XP_510921
379
43006
T202
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
T185
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
T203
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Rat
Rattus norvegicus
P63086
358
41257
T183
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
T193
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Frog
Xenopus laevis
P26696
361
41238
T188
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
T194
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
T248
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Honey Bee
Apis mellifera
XP_393029
371
42705
T187
H
N
H
A
G
F
L
T
E
Y
V
A
T
R
W
Nematode Worm
Caenorhab. elegans
P39745
444
50644
T256
T
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
T191
H
D
H
T
G
F
L
T
E
Y
V
A
T
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
T201
K
S
E
T
D
F
M
T
E
Y
V
V
T
R
W
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
T180
T
G
Q
Q
S
G
M
T
E
Y
V
A
T
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
86.6
93.3
100
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
93.3
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
93
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
79
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
100
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
86
8
0
0
0
0
0
0
0
0
0
% G
% His:
79
0
86
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% R
% Ser:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
15
0
0
86
0
0
0
100
0
0
0
0
100
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
100
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% W
% Tyr:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _