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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
42.73
Human Site:
Y30
Identified Species:
72.31
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
Y30
P
R
Y
T
N
L
S
Y
I
G
E
G
A
Y
G
Chimpanzee
Pan troglodytes
XP_510921
379
43006
P47
P
D
S
P
F
V
R
P
Q
Q
Q
P
L
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
Y30
P
R
Y
T
N
L
S
Y
I
G
E
G
A
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
Y48
P
R
Y
T
Q
L
Q
Y
I
G
E
G
A
Y
G
Rat
Rattus norvegicus
P63086
358
41257
Y28
P
R
Y
T
N
L
S
Y
I
G
E
G
A
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
Y38
P
R
Y
T
N
L
S
Y
I
G
E
G
A
Y
G
Frog
Xenopus laevis
P26696
361
41238
Y33
P
R
Y
I
N
L
A
Y
I
G
E
G
A
Y
G
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
Y39
P
R
Y
S
N
L
S
Y
I
G
G
G
A
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
Y93
P
R
Y
I
K
L
A
Y
I
G
E
G
A
Y
G
Honey Bee
Apis mellifera
XP_393029
371
42705
Y32
P
R
Y
T
N
L
S
Y
M
G
E
G
A
Y
G
Nematode Worm
Caenorhab. elegans
P39745
444
50644
Y101
P
R
Y
V
N
L
S
Y
I
G
E
G
A
Y
G
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
Y36
P
R
Y
V
T
L
N
Y
I
G
E
G
A
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
P48
K
Y
V
P
P
L
R
P
I
G
R
G
A
Y
G
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
L18
S
D
F
Q
L
K
S
L
L
G
E
G
A
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
13.3
N.A.
100
N.A.
86.6
100
N.A.
N.A.
100
86.6
86.6
N.A.
80
93.3
93.3
80
P-Site Similarity:
100
26.6
N.A.
100
N.A.
86.6
100
N.A.
N.A.
100
93.3
93.3
N.A.
86.6
100
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
0
0
93
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
79
0
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
93
8
93
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
79
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
86
0
8
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
58
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
86
0
0
15
8
0
0
15
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
8
0
8
0
8
8
8
0
0
0
0
% Q
% Arg:
0
79
0
0
0
0
15
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
8
8
0
0
58
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
43
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
15
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
79
0
0
0
0
79
0
0
0
0
0
93
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _