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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
32.73
Human Site:
Y43
Identified Species:
55.38
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
Y43
Y
G
M
V
C
S
A
Y
D
N
V
N
K
V
R
Chimpanzee
Pan troglodytes
XP_510921
379
43006
Y60
S
G
P
L
S
S
A
Y
D
H
V
R
K
T
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
Y43
Y
G
M
V
C
S
A
Y
D
N
V
N
K
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
Y61
Y
G
M
V
S
S
A
Y
D
H
V
R
K
T
R
Rat
Rattus norvegicus
P63086
358
41257
Y41
Y
G
M
V
C
S
A
Y
D
N
L
N
K
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
Y51
Y
G
M
V
C
S
A
Y
D
N
V
N
K
V
R
Frog
Xenopus laevis
P26696
361
41238
H46
Y
G
M
V
C
S
A
H
D
N
V
N
K
V
R
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
Y52
Y
G
M
V
C
S
A
Y
D
R
D
N
K
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
D106
Y
G
M
V
V
S
A
D
D
T
L
T
N
Q
R
Honey Bee
Apis mellifera
XP_393029
371
42705
Y45
Y
G
M
V
V
S
A
Y
D
N
V
T
K
T
K
Nematode Worm
Caenorhab. elegans
P39745
444
50644
L114
Y
G
M
V
A
S
A
L
D
T
I
T
R
D
R
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
V49
Y
G
M
V
C
S
A
V
D
T
R
H
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
T61
Y
G
I
V
C
A
A
T
N
S
E
T
G
E
E
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
T31
Y
G
V
V
C
S
A
T
H
K
P
T
G
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
53.3
N.A.
100
N.A.
73.3
93.3
N.A.
N.A.
100
93.3
86.6
N.A.
53.3
73.3
53.3
53.3
P-Site Similarity:
100
66.6
N.A.
100
N.A.
80
100
N.A.
N.A.
100
100
86.6
N.A.
60
80
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
86
0
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
22
8
0
% G
% His:
0
0
0
0
0
0
0
8
8
15
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
65
0
15
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
15
0
0
0
0
% L
% Met:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
43
0
43
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
15
8
0
72
% R
% Ser:
8
0
0
0
15
93
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
22
0
36
0
22
0
% T
% Val:
0
0
8
93
15
0
0
8
0
0
50
0
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _