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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
16.06
Human Site:
S1101
Identified Species:
29.44
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S1101
S
E
S
S
D
G
S
S
S
E
D
A
E
S
S
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1669
S
E
S
S
D
G
S
S
S
E
D
A
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1649
S
E
S
S
D
G
S
S
S
E
D
A
E
S
L
Dog
Lupus familis
XP_542659
1194
133696
S1111
S
P
S
S
G
T
S
S
G
E
D
T
E
C
G
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
S1086
S
E
S
P
Q
E
S
S
C
E
D
G
E
G
S
Rat
Rattus norvegicus
NP_001100380
862
96082
Q782
L
F
G
I
P
Y
I
Q
A
P
M
E
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
S1385
C
E
S
P
D
G
P
S
G
E
G
V
E
R
T
Chicken
Gallus gallus
NP_001029995
1118
126986
N1037
F
G
G
G
F
V
G
N
L
H
L
S
E
S
S
Frog
Xenopus laevis
P14629
1196
134188
K1116
G
F
I
G
I
E
L
K
T
L
S
S
K
A
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
L1153
A
P
P
T
D
D
D
L
A
I
A
D
V
A
T
Honey Bee
Apis mellifera
XP_393585
1047
119475
K967
Q
K
K
R
K
E
L
K
N
E
Q
A
L
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
L1022
A
E
F
K
G
H
G
L
K
T
L
K
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
I1366
D
D
S
V
D
A
S
I
N
D
C
P
S
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
93.3
93.3
53.3
N.A.
60
0
N.A.
46.6
20
0
N.A.
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
53.3
N.A.
60
13.3
N.A.
53.3
33.3
26.6
N.A.
N.A.
40
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
8
0
0
16
0
8
31
8
16
8
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% C
% Asp:
8
8
0
0
47
8
8
0
0
8
39
8
8
0
16
% D
% Glu:
0
47
0
0
0
24
0
0
0
54
0
8
47
16
0
% E
% Phe:
8
16
8
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
8
16
16
16
31
16
0
16
0
8
8
0
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
0
8
8
0
8
0
0
0
0
0
% I
% Lys:
0
8
8
8
8
0
0
16
8
0
0
8
8
0
8
% K
% Leu:
8
0
0
0
0
0
16
16
8
8
16
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% N
% Pro:
0
16
8
16
8
0
8
0
0
8
0
8
0
0
0
% P
% Gln:
8
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
39
0
54
31
0
0
47
47
24
0
8
16
8
31
31
% S
% Thr:
0
0
0
8
0
8
0
0
8
8
0
8
0
8
16
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _