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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC5 All Species: 13.33
Human Site: S1149 Identified Species: 24.44
UniProt: P28715 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28715 NP_000114.2 1186 133108 S1149 G A T T S S S S D S D D D G G
Chimpanzee Pan troglodytes XP_509723 1754 197217 S1717 G A T T S S S S D S D D D G G
Rhesus Macaque Macaca mulatta XP_001096257 1730 194783 D1697 T T S S S S D D D G G K E K T
Dog Lupus familis XP_542659 1194 133696 S1159 G A T T S S S S D D D G G G P
Cat Felis silvestris
Mouse Mus musculus P35689 1170 130839 S1134 G C V S T S S S S E D G E D K
Rat Rattus norvegicus NP_001100380 862 96082 E830 F N K N K F V E Y Y Q Y V D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513433 1466 166007 G1433 K M A S S S S G E D E E T P A
Chicken Gallus gallus NP_001029995 1118 126986 D1085 Y N S S S G E D E E L G N M I
Frog Xenopus laevis P14629 1196 134188 S1164 K V E S S S S S D D E D R T V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027230 1236 138998 S1201 E K C P R I P S S V E V I P Q
Honey Bee Apis mellifera XP_393585 1047 119475 V1015 N K L H A I E V F R K Q G L Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791943 1102 123652 N1070 L I A K A Y T N P A I D E S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ATY5 1479 165649 D1414 G G F C V D E D E T A E E N T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 64.7 74.5 N.A. 65.7 50 N.A. 49.7 54.7 50.3 N.A. N.A. 29.2 29.4 N.A. 22.9
Protein Similarity: 100 67.3 66.3 84.2 N.A. 77.2 57.7 N.A. 62 69.6 64.3 N.A. N.A. 50.8 48.8 N.A. 41.3
P-Site Identity: 100 100 20 73.3 N.A. 33.3 0 N.A. 20 6.6 40 N.A. N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 40 73.3 N.A. 53.3 0 N.A. 46.6 33.3 53.3 N.A. N.A. 13.3 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 16 0 16 0 0 0 0 8 8 0 0 0 8 % A
% Cys: 0 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 24 39 24 31 31 16 16 0 % D
% Glu: 8 0 8 0 0 0 24 8 24 16 24 16 31 0 8 % E
% Phe: 8 0 8 0 0 8 0 0 8 0 0 0 0 0 8 % F
% Gly: 39 8 0 0 0 8 0 8 0 8 8 24 16 24 16 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 16 0 0 0 0 8 0 8 0 8 % I
% Lys: 16 16 8 8 8 0 0 0 0 0 8 8 0 8 8 % K
% Leu: 8 0 8 0 0 0 0 0 0 0 8 0 0 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 16 0 8 0 0 0 8 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 8 0 0 8 0 8 0 0 0 0 16 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 0 0 16 39 54 54 47 47 16 16 0 0 0 8 0 % S
% Thr: 8 8 24 24 8 0 8 0 0 8 0 0 8 8 16 % T
% Val: 0 8 8 0 8 0 8 8 0 8 0 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 8 8 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _