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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
4.55
Human Site:
S1167
Identified Species:
8.33
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S1167
M
V
L
V
T
A
R
S
V
F
G
K
K
R
R
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1735
M
V
L
V
T
A
R
S
V
F
G
K
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
K1715
T
A
R
S
V
F
G
K
K
R
G
K
L
R
H
Dog
Lupus familis
XP_542659
1194
133696
F1177
L
V
T
A
R
S
V
F
G
K
R
K
G
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
V1152
V
L
V
T
A
R
P
V
F
G
K
K
K
L
K
Rat
Rattus norvegicus
NP_001100380
862
96082
L848
L
E
S
G
G
T
K
L
K
I
T
R
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
K1451
T
A
K
P
V
F
E
K
K
K
G
K
L
R
S
Chicken
Gallus gallus
NP_001029995
1118
126986
R1103
A
K
P
V
F
K
G
R
K
Q
K
S
Q
S
K
Frog
Xenopus laevis
P14629
1196
134188
K1182
A
K
P
V
F
Q
G
K
K
T
K
S
K
T
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
N1219
D
L
E
Q
M
R
L
N
K
A
K
A
A
E
I
Honey Bee
Apis mellifera
XP_393585
1047
119475
K1033
K
I
K
R
Y
I
R
K
I
K
K
E
A
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
G1088
Q
W
G
L
P
D
L
G
L
L
R
E
Y
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
E1432
D
A
E
I
L
K
M
E
S
E
E
Q
R
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
20
13.3
N.A.
13.3
0
N.A.
20
6.6
13.3
N.A.
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
20
33.3
N.A.
40
33.3
N.A.
20
20
13.3
N.A.
N.A.
13.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
24
0
8
8
16
0
0
0
8
0
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
16
0
0
0
8
8
0
8
8
16
0
16
0
% E
% Phe:
0
0
0
0
16
16
0
8
8
16
0
0
0
0
8
% F
% Gly:
0
0
8
8
8
0
24
8
8
8
31
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
8
0
8
0
0
8
8
0
0
0
0
8
% I
% Lys:
8
16
16
0
0
16
8
31
47
24
39
47
31
16
24
% K
% Leu:
16
16
16
8
8
0
16
8
8
8
0
0
16
16
16
% L
% Met:
16
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
8
8
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
8
0
8
0
0
0
8
0
8
8
0
8
% Q
% Arg:
0
0
8
8
8
16
24
8
0
8
16
8
16
31
16
% R
% Ser:
0
0
8
8
0
8
0
16
8
0
0
16
0
8
8
% S
% Thr:
16
0
8
8
16
8
0
0
0
8
8
0
0
8
0
% T
% Val:
8
24
8
31
16
0
8
8
16
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _