KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
20.91
Human Site:
S310
Identified Species:
38.33
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S310
V
D
S
E
S
L
P
S
S
S
K
M
H
G
M
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S878
V
D
S
E
S
L
P
S
S
S
K
M
H
G
M
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S858
V
D
S
E
S
L
P
S
S
S
K
M
H
S
M
Dog
Lupus familis
XP_542659
1194
133696
S309
E
D
S
K
P
L
P
S
S
S
E
M
H
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
S310
V
D
S
E
S
L
P
S
S
S
N
V
H
S
V
Rat
Rattus norvegicus
NP_001100380
862
96082
A28
A
L
E
G
K
V
L
A
V
D
I
S
I
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
P570
M
E
P
V
S
A
G
P
S
S
S
K
V
F
N
Chicken
Gallus gallus
NP_001029995
1118
126986
E277
N
E
G
G
F
V
K
E
M
E
S
R
R
I
I
Frog
Xenopus laevis
P14629
1196
134188
S314
K
V
D
S
P
P
Q
S
I
T
F
N
S
S
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
S318
L
K
K
K
A
M
E
S
T
K
Q
E
V
K
M
Honey Bee
Apis mellifera
XP_393585
1047
119475
I213
P
A
D
V
R
Y
E
I
L
T
D
L
K
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
S268
M
R
T
K
M
S
L
S
M
T
A
L
L
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
L303
L
A
Q
M
R
E
K
L
M
A
E
N
R
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
93.3
60
N.A.
73.3
0
N.A.
20
0
6.6
N.A.
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
86.6
20
N.A.
33.3
20
13.3
N.A.
N.A.
53.3
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
8
8
0
8
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
16
0
0
0
0
0
0
8
8
0
0
8
0
% D
% Glu:
8
16
8
31
0
8
16
8
0
8
16
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
0
8
16
0
0
8
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
8
0
8
8
8
% I
% Lys:
8
8
8
24
8
0
16
0
0
8
24
8
8
8
8
% K
% Leu:
16
8
0
0
0
39
16
8
8
0
0
16
8
0
8
% L
% Met:
16
0
0
8
8
8
0
0
24
0
0
31
0
0
31
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
16
0
0
8
% N
% Pro:
8
0
8
0
16
8
39
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
8
% Q
% Arg:
0
8
0
0
16
0
0
0
0
0
0
8
16
0
8
% R
% Ser:
0
0
39
8
39
8
0
62
47
47
16
8
8
31
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
24
0
0
0
0
8
% T
% Val:
31
8
0
16
0
16
0
0
8
0
0
8
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _