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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
17.58
Human Site:
S324
Identified Species:
32.22
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S324
M
S
F
D
V
K
S
S
P
C
E
K
L
K
T
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S892
M
S
F
D
V
K
S
S
P
C
E
K
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S872
M
S
F
D
V
K
P
S
P
C
E
K
L
K
T
Dog
Lupus familis
XP_542659
1194
133696
S323
R
S
F
D
V
K
S
S
P
C
E
E
L
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
S324
V
S
S
N
L
K
S
S
P
H
E
K
V
K
P
Rat
Rattus norvegicus
NP_001100380
862
96082
V42
L
N
Q
A
L
K
G
V
R
D
R
H
G
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
K584
N
P
T
L
F
E
A
K
L
P
P
H
E
K
T
Chicken
Gallus gallus
NP_001029995
1118
126986
Y291
I
S
E
D
S
S
H
Y
I
L
I
K
G
F
Q
Frog
Xenopus laevis
P14629
1196
134188
D328
Q
T
P
K
T
Y
L
D
L
K
L
A
S
A
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
P332
M
E
M
I
E
E
V
P
A
E
E
E
D
E
K
Honey Bee
Apis mellifera
XP_393585
1047
119475
G227
T
R
K
Q
S
S
W
G
R
L
H
E
M
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
Q282
A
Q
S
M
S
G
S
Q
V
D
A
G
R
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
A317
K
Y
Q
K
V
K
K
A
P
E
K
F
S
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
93.3
80
N.A.
53.3
6.6
N.A.
13.3
20
0
N.A.
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
26.6
N.A.
26.6
26.6
6.6
N.A.
N.A.
33.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
8
8
0
8
8
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% C
% Asp:
0
0
0
39
0
0
0
8
0
16
0
0
8
0
0
% D
% Glu:
0
8
8
0
8
16
0
0
0
16
47
24
8
16
8
% E
% Phe:
0
0
31
0
8
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
0
0
8
8
8
0
0
0
8
16
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
8
16
0
0
8
% H
% Ile:
8
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
8
0
8
16
0
54
8
8
0
8
8
39
0
47
8
% K
% Leu:
8
0
0
8
16
0
8
0
16
16
8
0
31
0
8
% L
% Met:
31
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
8
8
47
8
8
0
0
8
16
% P
% Gln:
8
8
16
8
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
8
8
0
0
0
0
0
0
16
0
8
0
8
0
0
% R
% Ser:
0
47
16
0
24
16
39
39
0
0
0
0
16
0
0
% S
% Thr:
8
8
8
0
8
0
0
0
0
0
0
0
0
0
31
% T
% Val:
8
0
0
0
39
0
8
8
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _