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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC5 All Species: 15.15
Human Site: S382 Identified Species: 27.78
UniProt: P28715 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28715 NP_000114.2 1186 133108 S382 P A A V D E G S I S P R T L S
Chimpanzee Pan troglodytes XP_509723 1754 197217 S950 P A A V D E G S I S P R T L S
Rhesus Macaque Macaca mulatta XP_001096257 1730 194783 S930 P A A V D E G S I S P R T L S
Dog Lupus familis XP_542659 1194 133696 V380 A P V S P L T V L A I Q K L L
Cat Felis silvestris
Mouse Mus musculus P35689 1170 130839 S382 G A T A D A G S I S P R T R A
Rat Rattus norvegicus NP_001100380 862 96082 D96 A K R R Q K K D S A S I D S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513433 1466 166007 S648 S E T V V E G S V S P R T L L
Chicken Gallus gallus NP_001029995 1118 126986 N345 L Q A E K D D N V I T A P P S
Frog Xenopus laevis P14629 1196 134188 N384 S G C E A E G N V S P R T L Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027230 1236 138998 R390 Y D S D Q E L R L N R A Q T K
Honey Bee Apis mellifera XP_393585 1047 119475 Q281 L D K L L K E Q G I F K P T D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791943 1102 123652 M336 A T S M D L K M Q K V M R K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ATY5 1479 165649 A374 F I F S S S F A G D K E V L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 64.7 74.5 N.A. 65.7 50 N.A. 49.7 54.7 50.3 N.A. N.A. 29.2 29.4 N.A. 22.9
Protein Similarity: 100 67.3 66.3 84.2 N.A. 77.2 57.7 N.A. 62 69.6 64.3 N.A. N.A. 50.8 48.8 N.A. 41.3
P-Site Identity: 100 100 100 6.6 N.A. 60 0 N.A. 60 13.3 46.6 N.A. N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 66.6 13.3 N.A. 66.6 33.3 60 N.A. N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 31 31 8 8 8 0 8 0 16 0 16 0 0 16 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 8 39 8 8 8 0 8 0 0 8 0 8 % D
% Glu: 0 8 0 16 0 47 8 0 0 0 0 8 0 0 0 % E
% Phe: 8 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 8 8 0 0 0 0 47 0 16 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 31 16 8 8 0 0 0 % I
% Lys: 0 8 8 0 8 16 16 0 0 8 8 8 8 8 8 % K
% Leu: 16 0 0 8 8 16 8 0 16 0 0 0 0 54 16 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 8 0 0 0 0 0 % N
% Pro: 24 8 0 0 8 0 0 0 0 0 47 0 16 8 0 % P
% Gln: 0 8 0 0 16 0 0 8 8 0 0 8 8 0 8 % Q
% Arg: 0 0 8 8 0 0 0 8 0 0 8 47 8 8 16 % R
% Ser: 16 0 16 16 8 8 0 39 8 47 8 0 0 8 31 % S
% Thr: 0 8 16 0 0 0 8 0 0 0 8 0 47 16 0 % T
% Val: 0 0 8 31 8 0 0 8 24 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _