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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
11.21
Human Site:
S453
Identified Species:
20.56
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S453
L
A
S
S
S
V
N
S
A
E
E
H
V
A
S
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1021
L
A
S
S
S
V
N
S
A
E
E
H
V
A
S
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1001
L
V
S
S
S
A
S
S
A
E
E
H
G
A
S
Dog
Lupus familis
XP_542659
1194
133696
G454
H
E
T
S
S
D
T
G
K
R
L
A
D
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
C453
S
V
T
E
V
K
E
C
V
T
S
G
S
S
A
Rat
Rattus norvegicus
NP_001100380
862
96082
E160
E
K
H
S
S
E
E
E
D
E
K
Q
W
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
E719
H
S
T
S
Q
V
S
E
Q
G
D
E
S
T
I
Chicken
Gallus gallus
NP_001029995
1118
126986
E409
Q
A
L
N
D
D
D
E
K
E
E
V
V
T
V
Frog
Xenopus laevis
P14629
1196
134188
S480
Y
T
R
S
K
P
V
S
Q
I
E
E
P
M
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
E457
M
A
D
N
S
I
E
E
A
K
L
I
S
Q
A
Honey Bee
Apis mellifera
XP_393585
1047
119475
T345
I
A
G
P
S
K
S
T
G
P
T
S
I
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
D400
L
D
D
K
A
S
K
D
E
A
V
K
A
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
N445
R
G
R
F
R
I
R
N
R
H
M
G
I
Q
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
73.3
13.3
N.A.
0
20
N.A.
13.3
26.6
20
N.A.
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
80
26.6
N.A.
20
33.3
N.A.
40
40
26.6
N.A.
N.A.
53.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
0
0
8
8
0
0
31
8
0
8
8
24
39
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
0
8
16
8
8
8
0
8
0
8
0
8
% D
% Glu:
8
8
0
8
0
8
24
31
8
39
39
16
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
8
8
8
0
16
8
0
0
% G
% His:
16
0
8
0
0
0
0
0
0
8
0
24
0
0
0
% H
% Ile:
8
0
0
0
0
16
0
0
0
8
0
8
16
0
8
% I
% Lys:
0
8
0
8
8
16
8
0
16
8
8
8
0
0
0
% K
% Leu:
31
0
8
0
0
0
0
0
0
0
16
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% M
% Asn:
0
0
0
16
0
0
16
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
8
0
0
8
8
0
% P
% Gln:
8
0
0
0
8
0
0
0
16
0
0
8
0
24
0
% Q
% Arg:
8
0
16
0
8
0
8
0
8
8
0
0
0
8
0
% R
% Ser:
8
8
24
54
54
8
24
31
0
0
8
8
24
8
24
% S
% Thr:
0
8
24
0
0
0
8
8
0
8
8
0
0
16
0
% T
% Val:
0
16
0
0
8
24
8
0
8
0
8
8
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _