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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
9.09
Human Site:
S489
Identified Species:
16.67
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S489
G
T
E
A
F
P
I
S
D
E
S
M
I
K
D
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1057
G
T
E
A
F
P
I
S
D
E
S
M
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1037
G
T
E
A
F
P
V
S
D
E
S
M
V
K
D
Dog
Lupus familis
XP_542659
1194
133696
K490
L
V
S
E
A
F
Q
K
S
D
E
F
T
V
K
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
A489
E
T
V
S
L
A
S
A
V
K
E
A
S
Q
I
Rat
Rattus norvegicus
NP_001100380
862
96082
L196
E
S
E
D
F
S
S
L
P
P
E
V
K
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
R755
S
V
Q
D
G
R
K
R
T
T
I
H
P
V
N
Chicken
Gallus gallus
NP_001029995
1118
126986
V445
E
E
D
Q
I
P
E
V
K
E
D
K
E
I
L
Frog
Xenopus laevis
P14629
1196
134188
K516
P
S
L
G
N
V
D
K
P
I
I
L
S
N
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
D493
K
V
E
I
V
D
T
D
T
D
S
D
L
E
E
Honey Bee
Apis mellifera
XP_393585
1047
119475
M381
N
F
K
F
T
S
K
M
N
N
D
T
E
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
V436
Y
A
P
V
P
D
D
V
V
C
L
D
R
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
F481
M
A
K
N
D
E
T
F
S
A
W
E
N
F
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
86.6
0
N.A.
6.6
13.3
N.A.
0
13.3
0
N.A.
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
33.3
33.3
N.A.
13.3
20
13.3
N.A.
N.A.
40
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
24
8
8
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
16
8
16
16
8
24
16
16
16
0
0
24
% D
% Glu:
24
8
39
8
0
8
8
0
0
31
24
8
16
8
24
% E
% Phe:
0
8
0
8
31
8
0
8
0
0
0
8
0
8
0
% F
% Gly:
24
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% H
% Ile:
0
0
0
8
8
0
16
0
0
8
16
0
16
8
8
% I
% Lys:
8
0
16
0
0
0
16
16
8
8
0
8
8
24
8
% K
% Leu:
8
0
8
0
8
0
0
8
0
0
8
8
8
0
8
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
24
0
0
0
% M
% Asn:
8
0
0
8
8
0
0
0
8
8
0
0
8
8
8
% N
% Pro:
8
0
8
0
8
31
0
0
16
8
0
0
8
0
8
% P
% Gln:
0
0
8
8
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% R
% Ser:
8
16
8
8
0
16
16
24
16
0
31
0
16
8
0
% S
% Thr:
0
31
0
0
8
0
16
0
16
8
0
8
8
0
8
% T
% Val:
0
24
8
8
8
8
8
16
16
0
0
8
8
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _