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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
9.7
Human Site:
S511
Identified Species:
17.78
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S511
E
S
A
V
V
R
H
S
D
A
P
G
L
P
N
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1079
E
S
A
V
V
R
H
S
D
A
P
G
L
P
N
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1059
E
S
A
V
V
R
H
S
D
A
L
G
L
P
S
Dog
Lupus familis
XP_542659
1194
133696
P512
S
E
S
T
M
V
M
P
S
D
A
P
G
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
P511
G
R
P
A
A
L
S
P
A
F
I
G
T
P
S
Rat
Rattus norvegicus
NP_001100380
862
96082
L218
F
T
K
R
R
R
T
L
F
E
A
M
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
S777
E
K
I
P
A
S
I
S
H
P
T
T
T
V
S
Chicken
Gallus gallus
NP_001029995
1118
126986
I467
N
Q
T
I
I
Q
D
I
E
F
E
Q
K
G
Q
Frog
Xenopus laevis
P14629
1196
134188
N538
R
I
P
L
L
P
V
N
M
S
M
R
E
T
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
E515
D
K
G
K
K
N
L
E
I
C
V
D
I
T
G
Honey Bee
Apis mellifera
XP_393585
1047
119475
K403
T
L
S
K
K
Y
L
K
K
N
I
T
N
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
N458
S
E
T
A
K
K
L
N
S
A
Q
S
L
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
V503
K
S
P
V
E
K
D
V
V
D
L
E
I
Q
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
86.6
0
N.A.
13.3
6.6
N.A.
13.3
0
0
N.A.
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
20
13.3
N.A.
20
26.6
26.6
N.A.
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
16
16
0
0
0
8
31
16
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
16
0
24
16
0
8
0
0
0
% D
% Glu:
31
16
0
0
8
0
0
8
8
8
8
8
8
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
31
8
8
8
% G
% His:
0
0
0
0
0
0
24
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
8
0
8
8
8
0
16
0
16
0
0
% I
% Lys:
8
16
8
16
24
16
0
8
8
0
0
0
8
0
0
% K
% Leu:
0
8
0
8
8
8
24
8
0
0
16
0
31
8
0
% L
% Met:
0
0
0
0
8
0
8
0
8
0
8
8
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
16
0
8
0
0
8
0
24
% N
% Pro:
0
0
24
8
0
8
0
16
0
8
16
8
8
39
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
8
8
0
8
16
% Q
% Arg:
8
8
0
8
8
31
0
0
0
0
0
8
0
0
0
% R
% Ser:
16
31
16
0
0
8
8
31
16
8
0
8
0
8
24
% S
% Thr:
8
8
16
8
0
0
8
0
0
0
8
16
16
16
0
% T
% Val:
0
0
0
31
24
8
8
8
8
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _