KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
12.12
Human Site:
S605
Identified Species:
22.22
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S605
D
N
V
E
N
V
V
S
F
N
A
K
E
H
E
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1173
D
N
V
E
N
V
V
S
F
N
A
K
E
H
E
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1153
G
N
V
E
N
V
V
S
F
N
T
K
E
H
E
Dog
Lupus familis
XP_542659
1194
133696
S606
S
N
L
E
D
A
V
S
F
N
G
K
E
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
P605
S
N
L
E
N
A
L
P
S
N
A
E
E
R
G
Rat
Rattus norvegicus
NP_001100380
862
96082
S312
L
E
S
L
P
S
S
S
K
E
H
S
V
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
V871
R
T
T
V
T
K
S
V
E
L
P
R
Q
V
I
Chicken
Gallus gallus
NP_001029995
1118
126986
K561
S
K
T
E
E
N
L
K
V
C
K
I
I
E
E
Frog
Xenopus laevis
P14629
1196
134188
Q632
L
D
V
T
Q
T
T
Q
P
S
G
G
S
E
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
K609
V
P
A
E
P
N
L
K
P
D
L
E
S
I
L
Honey Bee
Apis mellifera
XP_393585
1047
119475
E497
D
E
S
K
I
L
S
E
T
N
T
E
T
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
R552
I
S
V
S
G
K
S
R
T
R
S
L
E
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
K597
L
S
N
Q
H
I
P
K
D
I
S
I
A
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
86.6
60
N.A.
40
6.6
N.A.
0
13.3
6.6
N.A.
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
100
86.6
73.3
N.A.
60
6.6
N.A.
13.3
20
20
N.A.
N.A.
26.6
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
16
0
0
0
0
24
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
24
8
0
0
8
0
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
16
0
54
8
0
0
8
8
8
0
24
47
24
39
% E
% Phe:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
16
8
0
0
16
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
31
0
% H
% Ile:
8
0
0
0
8
8
0
0
0
8
0
16
8
8
16
% I
% Lys:
0
8
0
8
0
16
0
24
8
0
8
31
0
0
0
% K
% Leu:
24
0
16
8
0
8
24
0
0
8
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
8
0
31
16
0
0
0
47
0
0
0
8
0
% N
% Pro:
0
8
0
0
16
0
8
8
16
0
8
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
8
0
8
0
8
0
% R
% Ser:
24
16
16
8
0
8
31
39
8
8
16
8
16
8
0
% S
% Thr:
0
8
16
8
8
8
8
0
16
0
16
0
8
0
0
% T
% Val:
8
0
39
8
0
24
31
8
8
0
0
0
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _