KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
21.82
Human Site:
S662
Identified Species:
40
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
S662
I
E
V
Q
S
V
I
S
D
E
E
L
Q
A
E
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
S1230
I
E
V
Q
S
V
I
S
D
E
E
L
Q
A
E
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
S1210
I
E
V
Q
S
V
I
S
D
E
E
L
Q
A
E
Dog
Lupus familis
XP_542659
1194
133696
S663
I
E
V
Q
S
I
T
S
N
Y
E
V
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
S662
I
E
V
Q
S
V
V
S
N
S
E
L
Q
T
E
Rat
Rattus norvegicus
NP_001100380
862
96082
S369
E
S
G
E
G
G
Q
S
K
E
R
S
A
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
E928
L
V
E
I
D
S
E
E
S
A
S
D
G
S
F
Chicken
Gallus gallus
NP_001029995
1118
126986
V618
S
F
I
E
V
D
T
V
I
S
N
E
D
E
F
Frog
Xenopus laevis
P14629
1196
134188
S689
E
D
S
D
S
D
D
S
F
I
E
V
D
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
N666
V
K
N
I
T
L
D
N
V
K
L
S
N
S
V
Honey Bee
Apis mellifera
XP_393585
1047
119475
N554
S
K
E
N
T
I
I
N
N
Y
A
S
Q
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
L609
Q
D
I
L
K
E
L
L
K
K
K
E
D
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
S654
L
E
L
H
D
K
E
S
G
D
V
L
E
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
100
60
N.A.
73.3
13.3
N.A.
0
0
26.6
N.A.
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
86.6
20
N.A.
13.3
13.3
46.6
N.A.
N.A.
46.6
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
0
8
31
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
8
16
16
16
0
24
8
0
8
24
0
0
% D
% Glu:
16
47
16
16
0
8
16
8
0
31
47
16
8
16
47
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
16
% F
% Gly:
0
0
8
0
8
8
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
0
16
16
0
16
31
0
8
8
0
0
0
0
0
% I
% Lys:
0
16
0
0
8
8
0
0
16
16
8
0
0
0
8
% K
% Leu:
16
0
8
8
0
8
8
8
0
0
8
39
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
0
0
0
16
24
0
8
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
39
0
0
8
0
0
0
0
0
39
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
16
8
8
0
47
8
0
62
8
16
8
24
0
24
8
% S
% Thr:
0
0
0
0
16
0
16
0
0
0
0
0
0
8
0
% T
% Val:
8
8
39
0
8
31
8
8
8
0
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _