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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC5 All Species: 20.61
Human Site: S944 Identified Species: 37.78
UniProt: P28715 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28715 NP_000114.2 1186 133108 S944 L K P V V D D S K G S F L W G
Chimpanzee Pan troglodytes XP_509723 1754 197217 S1512 L K P V V D D S K G S F L W G
Rhesus Macaque Macaca mulatta XP_001096257 1730 194783 S1492 L K P V V D D S K G S F L W G
Dog Lupus familis XP_542659 1194 133696 S945 L K P V V D D S R G S F L W G
Cat Felis silvestris
Mouse Mus musculus P35689 1170 130839 A934 P N P A V A D A Y L R P V V D
Rat Rattus norvegicus NP_001100380 862 96082 A632 A A R E L I S A P E S L G P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513433 1466 166007 S1229 L R P V V D E S R G A F L W G
Chicken Gallus gallus NP_001029995 1118 126986 V886 S G F P N P A V A E A Y L K P
Frog Xenopus laevis P14629 1196 134188 V965 Q S F P N P A V A S A Y L K P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027230 1236 138998 L966 G I G A V T A L E I L A S F S
Honey Bee Apis mellifera XP_393585 1047 119475 N817 N F C S W I E N G K A T G P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791943 1102 123652 M872 H G V Y V D K M N E M E K K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ATY5 1479 165649 S1133 L N P Q V D L S T E K F S W G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 64.7 74.5 N.A. 65.7 50 N.A. 49.7 54.7 50.3 N.A. N.A. 29.2 29.4 N.A. 22.9
Protein Similarity: 100 67.3 66.3 84.2 N.A. 77.2 57.7 N.A. 62 69.6 64.3 N.A. N.A. 50.8 48.8 N.A. 41.3
P-Site Identity: 100 100 100 93.3 N.A. 20 6.6 N.A. 73.3 6.6 6.6 N.A. N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 33.3 20 N.A. 100 20 20 N.A. N.A. 20 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 16 0 8 24 16 16 0 31 8 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 54 39 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 0 0 16 0 8 31 0 8 0 0 0 % E
% Phe: 0 8 16 0 0 0 0 0 0 0 0 47 0 8 0 % F
% Gly: 8 16 8 0 0 0 0 0 8 39 0 0 16 0 54 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 16 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 31 0 0 0 0 8 0 24 8 8 0 8 24 0 % K
% Leu: 47 0 0 0 8 0 8 8 0 8 8 8 54 0 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % M
% Asn: 8 16 0 0 16 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 8 0 54 16 0 16 0 0 8 0 0 8 0 16 16 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 0 0 0 0 16 0 8 0 0 0 0 % R
% Ser: 8 8 0 8 0 0 8 47 0 8 39 0 16 0 8 % S
% Thr: 0 0 0 0 0 8 0 0 8 0 0 8 0 0 0 % T
% Val: 0 0 8 39 70 0 0 16 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 47 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _