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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
13.03
Human Site:
T468
Identified Species:
23.89
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
T468
T
N
E
G
R
E
P
T
D
S
V
P
K
E
Q
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
T1036
T
N
E
G
R
E
P
T
D
S
V
P
K
E
Q
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
T1016
T
N
E
G
R
E
P
T
D
S
V
P
K
E
Q
Dog
Lupus familis
XP_542659
1194
133696
C469
H
L
S
H
P
V
F
C
P
G
S
V
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
H468
N
E
Q
T
D
S
A
H
S
F
T
T
A
S
H
Rat
Rattus norvegicus
NP_001100380
862
96082
L175
R
M
D
Q
K
Q
A
L
Q
E
E
F
F
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
T734
K
D
G
K
E
Q
T
T
R
S
V
G
T
V
V
Chicken
Gallus gallus
NP_001029995
1118
126986
E424
R
T
D
R
V
Q
T
E
R
S
K
A
K
E
F
Frog
Xenopus laevis
P14629
1196
134188
N495
D
H
N
L
Q
G
D
N
C
N
V
P
N
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
S472
I
E
E
S
K
Q
L
S
Q
A
I
E
E
S
K
Honey Bee
Apis mellifera
XP_393585
1047
119475
N360
D
I
N
E
Y
E
L
N
D
D
W
D
S
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
D415
K
K
F
F
D
Q
L
D
A
K
I
S
P
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
L460
T
R
D
I
Q
R
N
L
H
L
M
K
E
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
20
20
13.3
N.A.
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
20
N.A.
33.3
33.3
40
N.A.
N.A.
53.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
0
8
8
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
16
8
24
0
16
0
8
8
31
8
0
8
0
8
0
% D
% Glu:
0
16
31
8
8
31
0
8
0
8
8
8
16
31
16
% E
% Phe:
0
0
8
8
0
0
8
0
0
8
0
8
8
0
8
% F
% Gly:
0
0
8
24
0
8
0
0
0
8
0
8
0
0
0
% G
% His:
8
8
0
8
0
0
0
8
8
0
0
0
0
8
8
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
16
0
0
0
8
% I
% Lys:
16
8
0
8
16
0
0
0
0
8
8
8
31
16
16
% K
% Leu:
0
8
0
8
0
0
24
16
0
8
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
24
16
0
0
0
8
16
0
8
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
0
24
0
8
0
0
31
8
0
0
% P
% Gln:
0
0
8
8
16
39
0
0
16
0
0
0
0
0
31
% Q
% Arg:
16
8
0
8
24
8
0
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
0
8
8
39
8
8
8
24
0
% S
% Thr:
31
8
0
8
0
0
16
31
0
0
8
8
8
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
0
39
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _