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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
13.33
Human Site:
T538
Identified Species:
24.44
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
T538
N
S
V
S
K
N
E
T
H
A
E
V
L
E
Q
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
T1106
N
S
V
S
K
N
E
T
H
A
E
V
L
E
Q
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
T1086
N
S
V
S
K
N
E
T
H
A
E
V
L
E
Q
Dog
Lupus familis
XP_542659
1194
133696
E539
S
S
S
V
S
R
N
E
T
Y
T
K
E
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
R538
T
L
A
P
P
T
T
R
T
H
S
D
Q
G
I
Rat
Rattus norvegicus
NP_001100380
862
96082
Q245
L
K
K
N
Y
L
N
Q
H
I
E
N
V
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
S804
D
L
I
P
T
S
T
S
T
H
S
V
L
A
Q
Chicken
Gallus gallus
NP_001029995
1118
126986
Y494
S
M
S
T
D
K
N
Y
S
C
V
D
D
N
G
Frog
Xenopus laevis
P14629
1196
134188
D565
R
Y
I
S
L
E
R
D
A
T
K
Q
G
F
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
I542
E
D
G
E
A
N
K
I
E
K
T
I
S
V
E
Honey Bee
Apis mellifera
XP_393585
1047
119475
E430
K
Q
I
L
T
L
L
E
N
N
G
E
M
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
T485
V
I
M
D
D
S
S
T
K
H
E
L
T
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
G530
I
S
F
D
H
D
G
G
G
K
D
L
N
D
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
100
6.6
N.A.
0
13.3
N.A.
20
0
6.6
N.A.
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
0
40
N.A.
46.6
13.3
20
N.A.
N.A.
26.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
8
24
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
8
8
0
16
16
8
0
8
0
0
8
16
8
8
0
% D
% Glu:
8
0
0
8
0
8
24
16
8
0
39
8
8
24
24
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
8
8
8
0
8
0
8
8
8
% G
% His:
0
0
0
0
8
0
0
0
31
24
0
0
0
0
0
% H
% Ile:
8
8
24
0
0
0
0
8
0
8
0
8
0
0
8
% I
% Lys:
8
8
8
0
24
8
8
0
8
16
8
8
0
0
16
% K
% Leu:
8
16
0
8
8
16
8
0
0
0
0
16
31
0
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
24
0
0
8
0
31
24
0
8
8
0
8
8
8
8
% N
% Pro:
0
0
0
16
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
0
8
8
8
31
% Q
% Arg:
8
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% R
% Ser:
16
39
16
31
8
16
8
8
8
0
16
0
8
0
8
% S
% Thr:
8
0
0
8
16
8
16
31
24
8
16
0
8
0
0
% T
% Val:
8
0
24
8
0
0
0
0
0
0
8
31
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _