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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC5 All Species: 9.09
Human Site: T920 Identified Species: 16.67
UniProt: P28715 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28715 NP_000114.2 1186 133108 T920 K V K K K L R T L Q L T P G F
Chimpanzee Pan troglodytes XP_509723 1754 197217 T1488 K V K K K L R T L Q L T P G F
Rhesus Macaque Macaca mulatta XP_001096257 1730 194783 T1468 K V K K K L R T L Q L T P G F
Dog Lupus familis XP_542659 1194 133696 K921 K V K K K L R K L Q L T P G F
Cat Felis silvestris
Mouse Mus musculus P35689 1170 130839 D910 K V A E N P Y D T K V K K K L
Rat Rattus norvegicus NP_001100380 862 96082 E608 V S S S N A E E H G D F Q K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513433 1466 166007 Q1205 K V K K K L R Q L Q L A P G F
Chicken Gallus gallus NP_001029995 1118 126986 N862 K N K K I R P N P R D T K V K
Frog Xenopus laevis P14629 1196 134188 N941 K D K K M R P N P N D T K V K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027230 1236 138998 L942 F N C N R G K L I Q L A C L V
Honey Bee Apis mellifera XP_393585 1047 119475 I793 G P V T A L E I L A A F P S E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791943 1102 123652 Q848 V D S D D D V Q R V Y M Q E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ATY5 1479 165649 N1109 Q H R K V S K N W H I P L T F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 64.7 74.5 N.A. 65.7 50 N.A. 49.7 54.7 50.3 N.A. N.A. 29.2 29.4 N.A. 22.9
Protein Similarity: 100 67.3 66.3 84.2 N.A. 77.2 57.7 N.A. 62 69.6 64.3 N.A. N.A. 50.8 48.8 N.A. 41.3
P-Site Identity: 100 100 100 93.3 N.A. 13.3 0 N.A. 86.6 26.6 26.6 N.A. N.A. 13.3 20 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 33.3 0 N.A. 86.6 33.3 26.6 N.A. N.A. 33.3 20 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 0 0 0 8 8 16 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 16 0 8 8 8 0 8 0 0 24 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 16 8 0 0 0 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 16 0 0 47 % F
% Gly: 8 0 0 0 0 8 0 0 0 8 0 0 0 39 0 % G
% His: 0 8 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 8 8 0 8 0 0 0 0 % I
% Lys: 62 0 54 62 39 0 16 8 0 8 0 8 24 16 16 % K
% Leu: 0 0 0 0 0 47 0 8 47 0 47 0 8 8 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 16 0 8 16 0 0 24 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 8 16 0 16 0 0 8 47 0 0 % P
% Gln: 8 0 0 0 0 0 0 16 0 47 0 0 16 0 0 % Q
% Arg: 0 0 8 0 8 16 39 0 8 8 0 0 0 0 0 % R
% Ser: 0 8 16 8 0 8 0 0 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 8 0 0 0 24 8 0 0 47 0 8 8 % T
% Val: 16 47 8 0 8 0 8 0 0 8 8 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _