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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC5
All Species:
17.27
Human Site:
Y965
Identified Species:
31.67
UniProt:
P28715
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28715
NP_000114.2
1186
133108
Y965
I
R
E
F
C
Q
R
Y
F
G
W
N
R
T
K
Chimpanzee
Pan troglodytes
XP_509723
1754
197217
Y1533
I
R
E
F
C
Q
R
Y
F
G
W
N
R
T
K
Rhesus Macaque
Macaca mulatta
XP_001096257
1730
194783
Y1513
I
R
E
F
C
Q
R
Y
F
G
W
N
R
T
K
Dog
Lupus familis
XP_542659
1194
133696
Y975
A
C
I
F
C
Q
R
Y
F
G
W
N
R
T
K
Cat
Felis silvestris
Mouse
Mus musculus
P35689
1170
130839
V954
F
L
W
G
K
P
D
V
D
K
I
R
E
F
C
Rat
Rattus norvegicus
NP_001100380
862
96082
G650
S
E
E
S
E
S
D
G
S
F
I
E
V
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513433
1466
166007
Y1250
I
R
Q
F
C
Q
R
Y
F
G
W
N
K
T
K
Chicken
Gallus gallus
NP_001029995
1118
126986
W904
E
T
R
G
S
F
I
W
G
K
P
D
V
E
Q
Frog
Xenopus laevis
P14629
1196
134188
W983
E
S
K
S
A
F
S
W
G
R
P
D
L
E
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027230
1236
138998
H1001
F
R
D
W
W
Q
A
H
K
C
S
N
L
P
P
Honey Bee
Apis mellifera
XP_393585
1047
119475
L835
L
R
T
K
L
Q
N
L
E
I
Q
K
G
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791943
1102
123652
R890
R
L
A
L
E
K
E
R
R
K
Q
Q
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ATY5
1479
165649
K1154
L
R
K
L
C
W
E
K
F
N
W
N
G
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
64.7
74.5
N.A.
65.7
50
N.A.
49.7
54.7
50.3
N.A.
N.A.
29.2
29.4
N.A.
22.9
Protein Similarity:
100
67.3
66.3
84.2
N.A.
77.2
57.7
N.A.
62
69.6
64.3
N.A.
N.A.
50.8
48.8
N.A.
41.3
P-Site Identity:
100
100
100
80
N.A.
0
6.6
N.A.
86.6
0
0
N.A.
N.A.
20
13.3
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
0
6.6
N.A.
100
20
26.6
N.A.
N.A.
40
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
47
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
8
0
0
0
16
0
8
0
0
16
0
0
0
% D
% Glu:
16
8
31
0
16
0
16
0
8
0
0
8
8
16
0
% E
% Phe:
16
0
0
39
0
16
0
0
47
8
0
0
0
16
0
% F
% Gly:
0
0
0
16
0
0
0
8
16
39
0
0
16
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
31
0
8
0
0
0
8
0
0
8
16
0
0
0
0
% I
% Lys:
0
0
16
8
8
8
0
8
8
24
0
8
16
16
47
% K
% Leu:
16
16
0
16
8
0
0
8
0
0
0
0
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
54
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
16
0
0
8
16
% P
% Gln:
0
0
8
0
0
54
0
0
0
0
16
8
0
8
16
% Q
% Arg:
8
54
8
0
0
0
39
8
8
8
0
8
31
0
0
% R
% Ser:
8
8
0
16
8
8
8
0
8
0
8
0
0
0
16
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
0
0
39
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
16
0
0
% V
% Trp:
0
0
8
8
8
8
0
16
0
0
47
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _