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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL1 All Species: 25.15
Human Site: S489 Identified Species: 46.11
UniProt: P28749 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28749 NP_002886.2 1068 120847 S489 R L H G M D M S V L L E Q D I
Chimpanzee Pan troglodytes XP_001139919 1068 120960 S489 R L H G M D M S V L L E Q D I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534412 1068 120563 S489 R L H G M D M S V L L E Q D I
Cat Felis silvestris
Mouse Mus musculus Q64701 1063 119481 S489 R L H G M D M S V L L E Q D I
Rat Rattus norvegicus O55081 1135 127799 S517 R L G D M D L S G V L E Q D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 S460 R L G D T D L S G I L E Q D A
Chicken Gallus gallus Q90600 921 104417 A368 P Q T P V R A A M N T I Q Q L
Frog Xenopus laevis NP_001084880 998 113114 T443 R L H G K D L T A L L E Q D I
Zebra Danio Brachydanio rerio NP_001124082 1058 120023 A490 R L Q G K D W A V L L E Q E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 T292 S S F F Q A S T I Y G N K D T
Honey Bee Apis mellifera XP_395096 1006 113492 D449 N A N E T T S D F G R K R L Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q3LXA7 1010 111475 L435 L R N T V S P L P S R P S G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 K438 P G L E H F L K S C D R D I T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 95 N.A. 90.3 48.9 N.A. 52.8 22.1 63.9 63.2 N.A. 25.4 43.1 N.A. N.A.
Protein Similarity: 100 99.8 N.A. 98 N.A. 95.6 65.9 N.A. 69.7 37.8 77.3 77 N.A. 44.4 63.2 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 60 N.A. 53.3 6.6 73.3 60 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 73.3 N.A. 66.6 33.3 86.6 80 N.A. 26.6 20 N.A. N.A.
Percent
Protein Identity: N.A. 25 N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. 43.9 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 16 8 0 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 16 0 62 0 8 0 0 8 0 8 62 0 % D
% Glu: 0 0 0 16 0 0 0 0 0 0 0 62 0 8 8 % E
% Phe: 0 0 8 8 0 8 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 8 16 47 0 0 0 0 16 8 8 0 0 8 0 % G
% His: 0 0 39 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 8 0 8 0 8 39 % I
% Lys: 0 0 0 0 16 0 0 8 0 0 0 8 8 0 0 % K
% Leu: 8 62 8 0 0 0 31 8 0 47 62 0 0 8 8 % L
% Met: 0 0 0 0 39 0 31 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 16 0 0 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 16 0 0 8 0 0 8 0 8 0 0 8 0 0 0 % P
% Gln: 0 8 8 0 8 0 0 0 0 0 0 0 70 8 0 % Q
% Arg: 62 8 0 0 0 8 0 0 0 0 16 8 8 0 0 % R
% Ser: 8 8 0 0 0 8 16 47 8 8 0 0 8 0 0 % S
% Thr: 0 0 8 8 16 8 0 16 0 0 8 0 0 0 16 % T
% Val: 0 0 0 0 16 0 0 0 39 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _