Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL1 All Species: 25.15
Human Site: S548 Identified Species: 46.11
UniProt: P28749 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28749 NP_002886.2 1068 120847 S548 I R S E E G L S R D M V K H L
Chimpanzee Pan troglodytes XP_001139919 1068 120960 S548 I R S E E G L S R D M V K H L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534412 1068 120563 S548 I R S E E G L S R D M V K H L
Cat Felis silvestris
Mouse Mus musculus Q64701 1063 119481 S548 I R S E E G L S R D M V K H L
Rat Rattus norvegicus O55081 1135 127799 C576 I R A E D G L C R E V V K H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 C519 I R A E D G L C R E V V K H L
Chicken Gallus gallus Q90600 921 104417 G427 F A E A V G Q G C A E I G S Q
Frog Xenopus laevis NP_001084880 998 113114 S502 I R S E D G L S R D M V K H L
Zebra Danio Brachydanio rerio NP_001124082 1058 120023 S549 I R S E E G L S R D M V K H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 L351 T A L N D Q S L R P P V T P L
Honey Bee Apis mellifera XP_395096 1006 113492 K508 E I V I Y S Y K S N D K I F P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q3LXA7 1010 111475 T494 S R M D A I W T E Q R K M E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 Y497 L E A C K L Y Y R V L E A M C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 95 N.A. 90.3 48.9 N.A. 52.8 22.1 63.9 63.2 N.A. 25.4 43.1 N.A. N.A.
Protein Similarity: 100 99.8 N.A. 98 N.A. 95.6 65.9 N.A. 69.7 37.8 77.3 77 N.A. 44.4 63.2 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 66.6 N.A. 66.6 6.6 93.3 100 N.A. 20 0 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 93.3 13.3 100 100 N.A. 26.6 6.6 N.A. N.A.
Percent
Protein Identity: N.A. 25 N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. 43.9 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 24 8 8 0 0 0 0 8 0 0 8 0 8 % A
% Cys: 0 0 0 8 0 0 0 16 8 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 31 0 0 0 0 47 8 0 0 0 0 % D
% Glu: 8 8 8 62 39 0 0 0 8 16 8 8 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 70 0 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 62 0 % H
% Ile: 62 8 0 8 0 8 0 0 0 0 0 8 8 0 0 % I
% Lys: 0 0 0 0 8 0 0 8 0 0 0 16 62 0 0 % K
% Leu: 8 0 8 0 0 8 62 8 0 0 8 0 0 0 70 % L
% Met: 0 0 8 0 0 0 0 0 0 0 47 0 8 8 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 8 % P
% Gln: 0 0 0 0 0 8 8 0 0 8 0 0 0 0 8 % Q
% Arg: 0 70 0 0 0 0 0 0 77 0 8 0 0 0 0 % R
% Ser: 8 0 47 0 0 8 8 47 8 0 0 0 0 8 0 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % T
% Val: 0 0 8 0 8 0 0 0 0 8 16 70 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 16 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _