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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBL1
All Species:
10.61
Human Site:
S686
Identified Species:
19.44
UniProt:
P28749
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28749
NP_002886.2
1068
120847
S686
T
K
L
K
I
A
P
S
S
S
I
T
A
E
N
Chimpanzee
Pan troglodytes
XP_001139919
1068
120960
S686
T
K
L
K
I
A
P
S
S
S
I
T
A
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534412
1068
120563
S686
T
K
L
K
I
A
P
S
S
S
I
T
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64701
1063
119481
P685
G
T
K
L
K
I
A
P
S
S
V
T
A
E
S
Rat
Rattus norvegicus
O55081
1135
127799
T730
L
V
T
M
A
T
A
T
V
T
A
N
N
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520195
1071
120785
A665
T
L
V
T
M
A
T
A
T
V
T
A
N
N
G
Chicken
Gallus gallus
Q90600
921
104417
D558
E
S
L
A
W
Q
S
D
S
P
L
F
D
L
I
Frog
Xenopus laevis
NP_001084880
998
113114
I633
P
D
I
T
R
I
R
I
A
I
S
P
S
P
V
Zebra Danio
Brachydanio rerio
NP_001124082
1058
120023
I683
S
V
T
P
I
K
I
I
P
S
G
M
E
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24472
845
96808
A482
I
F
N
I
T
L
M
A
C
C
V
E
L
V
L
Honey Bee
Apis mellifera
XP_395096
1006
113492
V639
S
P
V
A
A
S
G
V
A
K
K
R
L
F
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q3LXA7
1010
111475
S628
P
A
L
S
V
E
I
S
R
L
G
L
L
A
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKZ3
1013
112157
M628
L
G
L
L
A
E
P
M
P
S
L
D
A
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
95
N.A.
90.3
48.9
N.A.
52.8
22.1
63.9
63.2
N.A.
25.4
43.1
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
98
N.A.
95.6
65.9
N.A.
69.7
37.8
77.3
77
N.A.
44.4
63.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
33.3
0
N.A.
13.3
13.3
0
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
46.6
13.3
N.A.
40
20
20
20
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
25
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
43.9
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
24
31
16
16
16
0
8
8
39
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
0
8
8
0
0
% D
% Glu:
8
0
0
0
0
16
0
0
0
0
0
8
8
31
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
8
8
0
0
0
0
8
0
0
0
16
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
31
16
16
16
0
8
24
0
0
8
8
% I
% Lys:
0
24
8
24
8
8
0
0
0
8
8
0
0
0
0
% K
% Leu:
16
8
47
16
0
8
0
0
0
8
16
8
24
8
8
% L
% Met:
0
0
0
8
8
0
8
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
16
16
24
% N
% Pro:
16
8
0
8
0
0
31
8
16
8
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
8
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
16
8
0
8
0
8
8
31
39
47
8
0
8
0
16
% S
% Thr:
31
8
16
16
8
8
8
8
8
8
8
31
0
0
0
% T
% Val:
0
16
16
0
8
0
0
8
8
8
16
0
0
8
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _