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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBL1
All Species:
30.3
Human Site:
Y274
Identified Species:
55.56
UniProt:
P28749
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28749
NP_002886.2
1068
120847
Y274
K
E
H
Y
F
K
P
Y
I
S
K
L
F
D
R
Chimpanzee
Pan troglodytes
XP_001139919
1068
120960
Y274
K
E
H
Y
F
K
P
Y
I
S
K
L
F
D
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534412
1068
120563
Y274
K
E
H
Y
F
K
P
Y
I
S
K
L
F
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64701
1063
119481
Y274
K
E
H
Y
F
K
P
Y
I
S
K
L
F
D
K
Rat
Rattus norvegicus
O55081
1135
127799
Y298
K
Q
H
F
W
K
P
Y
I
R
K
L
F
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520195
1071
120785
Y241
K
E
H
F
W
K
P
Y
I
R
K
L
F
D
K
Chicken
Gallus gallus
Q90600
921
104417
P165
G
L
I
Y
L
E
Q
P
S
S
E
I
S
A
E
Frog
Xenopus laevis
NP_001084880
998
113114
Y229
K
E
H
Y
F
K
P
Y
I
A
K
L
H
D
K
Zebra Danio
Brachydanio rerio
NP_001124082
1058
120023
Y270
K
E
H
Y
F
K
P
Y
I
K
T
L
F
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24472
845
96808
Q89
S
T
P
T
V
T
G
Q
N
A
V
V
K
G
N
Honey Bee
Apis mellifera
XP_395096
1006
113492
L246
T
A
N
C
I
V
S
L
L
C
E
R
H
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q3LXA7
1010
111475
E221
D
L
V
T
S
T
N
E
L
V
S
V
L
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKZ3
1013
112157
C232
I
L
I
I
H
V
P
C
R
F
R
N
F
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
95
N.A.
90.3
48.9
N.A.
52.8
22.1
63.9
63.2
N.A.
25.4
43.1
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
98
N.A.
95.6
65.9
N.A.
69.7
37.8
77.3
77
N.A.
44.4
63.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
60
N.A.
73.3
13.3
80
73.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
93.3
33.3
93.3
86.6
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
25
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
43.9
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
16
0
0
0
16
8
% A
% Cys:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% D
% Glu:
0
54
0
0
0
8
0
8
0
0
16
0
0
24
8
% E
% Phe:
0
0
0
16
47
0
0
0
0
8
0
0
62
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
62
0
8
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
8
0
16
8
8
0
0
0
62
0
0
8
0
0
8
% I
% Lys:
62
0
0
0
0
62
0
0
0
8
54
0
8
0
39
% K
% Leu:
0
24
0
0
8
0
0
8
16
0
0
62
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
8
% N
% Pro:
0
0
8
0
0
0
70
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
16
8
8
0
0
24
% R
% Ser:
8
0
0
0
8
0
8
0
8
39
8
0
8
8
0
% S
% Thr:
8
8
0
16
0
16
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
0
8
16
0
0
0
8
8
16
0
0
8
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
54
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _