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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
10.61
Human Site:
S262
Identified Species:
25.93
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
S262
L
I
Q
S
K
C
L
S
K
E
N
A
T
T
D
Chimpanzee
Pan troglodytes
XP_511549
501
53936
F217
G
A
W
G
C
C
P
F
T
Q
A
V
C
C
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
T308
L
A
H
A
R
C
L
T
A
T
G
S
H
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
S261
L
I
Q
S
K
C
L
S
K
N
Y
T
T
D
L
Rat
Rattus norvegicus
P23785
588
63351
S260
L
I
Q
S
K
C
I
S
K
D
Y
T
T
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
P233
P
P
G
F
R
S
G
P
G
S
G
A
C
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
S262
L
V
H
K
K
C
V
S
R
N
G
E
G
P
L
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
D321
V
A
A
S
S
C
D
D
P
T
E
L
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
F74
H
S
S
F
S
F
I
F
S
I
K
I
M
R
L
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
K91
P
D
G
N
T
C
C
K
L
A
S
G
Q
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
6.6
N.A.
20
N.A.
66.6
60
N.A.
6.6
N.A.
26.6
13.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
20
N.A.
46.6
N.A.
66.6
73.3
N.A.
13.3
N.A.
46.6
26.6
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
10
10
0
0
0
0
10
10
10
20
0
10
0
% A
% Cys:
0
0
0
0
10
80
10
0
0
0
0
0
20
10
0
% C
% Asp:
0
10
0
0
0
0
10
10
0
10
0
0
0
20
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
10
% E
% Phe:
0
0
0
20
0
10
0
20
0
0
0
0
0
0
0
% F
% Gly:
10
0
20
10
0
0
10
0
10
0
30
10
10
0
10
% G
% His:
10
0
20
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
30
0
0
0
0
20
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
10
40
0
0
10
30
0
10
0
0
0
0
% K
% Leu:
50
0
0
0
0
0
30
0
10
0
0
10
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
20
10
0
0
0
0
% N
% Pro:
20
10
0
0
0
0
10
10
10
0
0
0
0
20
0
% P
% Gln:
0
0
30
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
0
0
20
0
0
0
10
0
0
0
0
10
0
% R
% Ser:
0
10
10
40
20
10
0
40
10
10
10
10
10
0
10
% S
% Thr:
0
0
0
0
10
0
0
10
10
20
0
20
30
10
0
% T
% Val:
10
10
0
0
0
0
10
0
0
0
0
10
0
10
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
20
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _