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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
4.85
Human Site:
S353
Identified Species:
11.85
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
S353
E
K
A
P
A
H
L
S
L
P
D
P
Q
A
L
Chimpanzee
Pan troglodytes
XP_511549
501
53936
A302
G
C
C
P
I
P
E
A
V
C
C
S
D
H
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
T394
E
N
A
T
D
L
L
T
K
L
P
A
H
T
V
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
R351
K
K
V
I
A
P
L
R
L
P
D
P
Q
I
L
Rat
Rattus norvegicus
P23785
588
63351
S350
K
K
V
T
A
S
L
S
L
P
D
P
Q
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
C318
P
I
P
E
A
V
C
C
P
D
Q
V
H
C
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
W418
K
G
A
L
S
I
P
W
L
G
K
T
P
A
L
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
K415
R
I
S
V
P
M
V
K
K
I
P
A
V
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
M159
A
D
E
K
H
V
P
M
K
K
K
K
P
A
R
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
P176
P
S
S
S
T
C
C
P
L
M
A
S
G
E
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
6.6
N.A.
20
N.A.
60
66.6
N.A.
6.6
N.A.
26.6
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
20
N.A.
33.3
N.A.
66.6
73.3
N.A.
6.6
N.A.
40
26.6
N.A.
N.A.
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
0
40
0
0
10
0
0
10
20
0
30
0
% A
% Cys:
0
10
10
0
0
10
20
10
0
10
10
0
0
10
10
% C
% Asp:
0
10
0
0
10
0
0
0
0
10
30
0
10
0
0
% D
% Glu:
20
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
20
10
0
% H
% Ile:
0
20
0
10
10
10
0
0
0
10
0
0
0
20
0
% I
% Lys:
30
30
0
10
0
0
0
10
30
10
20
10
0
0
0
% K
% Leu:
0
0
0
10
0
10
40
0
50
10
0
0
0
0
40
% L
% Met:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
0
10
20
10
20
20
10
10
30
20
30
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
30
0
10
% Q
% Arg:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
10
20
10
10
10
0
20
0
0
0
20
0
10
0
% S
% Thr:
0
0
0
20
10
0
0
10
0
0
0
10
0
10
0
% T
% Val:
0
0
20
10
0
20
10
0
10
0
0
10
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _