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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
0
Human Site:
S375
Identified Species:
0
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
S375
N
V
S
S
C
P
S
S
D
T
C
C
Q
L
T
Chimpanzee
Pan troglodytes
XP_511549
501
53936
G322
G
Y
T
C
V
A
E
G
Q
C
Q
R
G
S
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
G415
M
E
V
S
C
P
D
G
Y
T
C
C
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
N373
D
F
T
R
C
P
T
N
N
T
C
C
K
L
N
Rat
Rattus norvegicus
P23785
588
63351
N372
D
F
S
S
C
P
S
N
N
T
C
C
R
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
H338
C
S
G
Q
G
Q
C
H
Q
G
A
L
R
V
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
G517
D
S
F
S
C
N
D
G
Q
T
C
C
R
M
Q
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
G438
E
T
S
S
C
P
T
G
T
T
C
C
K
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
C179
N
Q
F
N
E
V
V
C
P
D
K
A
S
K
C
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
D196
H
N
A
V
C
C
D
D
H
I
H
C
C
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
0
N.A.
46.6
N.A.
40
60
N.A.
0
N.A.
33.3
60
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
6.6
N.A.
53.3
N.A.
80
93.3
N.A.
13.3
N.A.
53.3
73.3
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
10
10
0
0
0
% A
% Cys:
10
0
0
10
70
10
10
10
0
10
60
70
10
0
10
% C
% Asp:
30
0
0
0
0
0
30
10
10
10
0
0
0
0
0
% D
% Glu:
10
10
0
0
10
0
10
0
0
0
0
0
0
0
10
% E
% Phe:
0
20
20
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
0
0
40
0
10
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
20
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
50
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
20
10
0
10
0
10
0
20
20
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
50
0
0
10
0
0
0
0
10
10
% P
% Gln:
0
10
0
10
0
10
0
0
30
0
10
0
10
0
20
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
10
40
0
0
% R
% Ser:
0
20
30
50
0
0
20
10
0
0
0
0
10
10
20
% S
% Thr:
0
10
20
0
0
0
20
0
10
60
0
0
0
0
20
% T
% Val:
0
10
10
10
10
10
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _