KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
2.12
Human Site:
S420
Identified Species:
5.19
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
S420
E
G
Q
C
Q
R
G
S
E
I
V
A
G
L
E
Chimpanzee
Pan troglodytes
XP_511549
501
53936
S367
V
G
Q
T
C
C
P
S
L
G
G
S
W
A
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
N460
A
K
G
T
C
E
Q
N
A
P
Q
M
P
W
M
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
D418
Q
G
Y
C
Q
K
G
D
T
M
V
A
G
L
E
Rat
Rattus norvegicus
P23785
588
63351
D417
E
G
Y
C
Q
K
G
D
R
M
V
A
G
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
W383
C
P
S
Q
S
G
G
W
A
C
C
Q
L
P
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
R562
R
G
T
C
V
L
G
R
L
N
L
P
G
L
M
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
S483
A
Q
S
S
C
V
R
S
G
L
P
S
M
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
C224
C
C
P
N
G
F
T
C
H
G
Q
F
C
S
Q
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
P241
E
G
Q
E
E
P
K
P
E
V
K
V
H
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
20
N.A.
0
N.A.
60
66.6
N.A.
6.6
N.A.
33.3
6.6
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
26.6
N.A.
6.6
N.A.
80
80
N.A.
6.6
N.A.
40
20
N.A.
N.A.
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
20
0
0
30
0
20
0
% A
% Cys:
20
10
0
40
30
10
0
10
0
10
10
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
0
0
0
10
0
% D
% Glu:
30
0
0
10
10
10
0
0
20
0
0
0
0
0
30
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
60
10
0
10
10
50
0
10
20
10
0
40
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
20
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
20
10
10
0
10
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
10
10
0
20
% M
% Asn:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
20
% N
% Pro:
0
10
10
0
0
10
10
10
0
10
10
10
10
10
0
% P
% Gln:
10
10
30
10
30
0
10
0
0
0
20
10
0
0
10
% Q
% Arg:
10
0
0
0
0
10
10
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
20
10
10
0
0
30
0
0
0
20
0
10
0
% S
% Thr:
0
0
10
20
0
0
10
0
10
0
0
0
0
0
0
% T
% Val:
10
0
0
0
10
10
0
0
0
10
30
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
10
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _