KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
5.45
Human Site:
S435
Identified Species:
13.33
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
S435
K
M
P
A
R
R
A
S
L
S
H
P
R
D
I
Chimpanzee
Pan troglodytes
XP_511549
501
53936
C382
C
Q
L
P
H
A
V
C
C
E
D
R
Q
H
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
Q475
V
Q
A
P
A
R
L
Q
L
L
N
P
Q
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
T433
K
I
P
A
R
Q
T
T
P
L
Q
I
G
D
I
Rat
Rattus norvegicus
P23785
588
63351
T432
K
M
P
V
R
Q
T
T
L
L
Q
H
G
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
Q398
A
V
C
C
E
D
R
Q
H
C
C
P
W
G
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
D577
K
V
P
A
L
S
S
D
G
N
W
C
D
E
S
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
R498
F
R
K
E
P
A
L
R
E
T
Q
R
V
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
L239
N
F
A
M
I
P
H
L
R
K
F
A
S
T
S
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
D256
K
H
L
L
F
Q
P
D
E
P
R
T
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
0
N.A.
20
N.A.
40
46.6
N.A.
6.6
N.A.
20
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
6.6
N.A.
33.3
N.A.
60
60
N.A.
13.3
N.A.
46.6
13.3
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
30
10
20
10
0
0
0
0
10
0
10
0
% A
% Cys:
10
0
10
10
0
0
0
10
10
10
10
10
0
0
10
% C
% Asp:
0
0
0
0
0
10
0
20
0
0
10
0
10
30
10
% D
% Glu:
0
0
0
10
10
0
0
0
20
10
0
0
0
20
0
% E
% Phe:
10
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
30
10
0
% G
% His:
0
10
0
0
10
0
10
0
10
0
10
10
0
10
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
30
% I
% Lys:
50
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
20
10
10
0
20
10
30
30
0
0
0
0
0
% L
% Met:
0
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
40
20
10
10
10
0
10
10
0
30
0
0
0
% P
% Gln:
0
20
0
0
0
30
0
20
0
0
30
0
20
0
0
% Q
% Arg:
0
10
0
0
30
20
10
10
10
0
10
20
10
0
0
% R
% Ser:
0
0
0
0
0
10
10
10
0
10
0
0
10
10
20
% S
% Thr:
0
0
0
0
0
0
20
20
0
10
0
10
0
10
10
% T
% Val:
10
20
0
10
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _