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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
18.48
Human Site:
T220
Identified Species:
45.19
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
T220
S
R
C
P
D
G
S
T
C
C
E
L
P
S
G
Chimpanzee
Pan troglodytes
XP_511549
501
53936
T175
C
L
S
K
E
N
A
T
T
D
L
L
T
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
T266
F
L
C
P
N
S
S
T
C
C
T
M
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
T219
T
Q
C
P
D
D
S
T
C
C
E
L
P
T
G
Rat
Rattus norvegicus
P23785
588
63351
T218
T
Q
C
P
D
D
S
T
C
C
E
L
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
Q191
C
C
S
L
G
F
G
Q
W
G
C
C
P
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
T220
T
S
C
P
D
G
S
T
C
C
E
K
V
D
H
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
T279
V
A
C
S
S
G
T
T
C
C
K
T
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
Y32
I
L
Y
F
N
I
K
Y
F
S
F
H
T
F
I
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
E49
T
L
A
M
F
L
Q
E
P
A
H
K
E
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
13.3
N.A.
46.6
N.A.
73.3
73.3
N.A.
13.3
N.A.
60
46.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
26.6
N.A.
60
N.A.
93.3
93.3
N.A.
13.3
N.A.
66.6
60
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
20
10
60
0
0
0
0
0
60
60
10
10
0
0
0
% C
% Asp:
0
0
0
0
40
20
0
0
0
10
0
0
0
20
0
% D
% Glu:
0
0
0
0
10
0
0
10
0
0
40
0
10
10
0
% E
% Phe:
10
0
0
10
10
10
0
0
10
0
10
0
0
10
0
% F
% Gly:
0
0
0
0
10
30
10
0
0
10
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
10
20
0
20
0
% K
% Leu:
0
40
0
10
0
10
0
0
0
0
10
40
10
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
0
0
0
0
10
0
0
0
50
0
10
% P
% Gln:
0
20
0
0
0
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
20
10
10
10
50
0
0
10
0
0
0
20
10
% S
% Thr:
40
0
0
0
0
0
10
70
10
0
10
10
20
20
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _