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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRN
All Species:
9.09
Human Site:
Y229
Identified Species:
22.22
UniProt:
P28799
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28799
NP_002078.1
593
63544
Y229
C
E
L
P
S
G
K
Y
G
C
C
P
M
P
N
Chimpanzee
Pan troglodytes
XP_511549
501
53936
A184
D
L
L
T
K
L
P
A
H
T
V
G
D
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537620
642
67990
W275
C
T
M
L
D
G
S
W
G
C
C
P
M
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P28798
589
63440
Y228
C
E
L
P
T
G
K
Y
G
C
C
P
M
P
N
Rat
Rattus norvegicus
P23785
588
63351
Y227
C
E
L
P
T
G
K
Y
G
C
C
P
M
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518385
517
54097
V200
G
C
C
P
S
P
Q
V
P
R
A
P
G
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085281
724
76776
H229
C
E
K
V
D
H
T
H
G
C
C
S
I
L
S
Zebra Danio
Brachydanio rerio
NP_997903
729
78431
W288
C
K
T
P
E
G
S
W
A
C
C
P
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492981
358
39736
E41
S
F
H
T
F
I
A
E
L
D
Q
T
I
I
I
Sea Urchin
Strong. purpuratus
XP_780679
375
39819
V58
A
H
K
E
K
S
V
V
P
W
Y
E
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
41.1
N.A.
75.2
75.2
N.A.
44.3
N.A.
39.2
34.8
N.A.
N.A.
N.A.
25.7
24.7
Protein Similarity:
100
84.3
N.A.
51.5
N.A.
84.8
84.8
N.A.
51.9
N.A.
49
46.2
N.A.
N.A.
N.A.
35
36.2
P-Site Identity:
100
6.6
N.A.
53.3
N.A.
93.3
93.3
N.A.
20
N.A.
33.3
46.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
6.6
N.A.
66.6
N.A.
100
100
N.A.
26.6
N.A.
53.3
66.6
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
10
10
0
10
0
0
0
0
% A
% Cys:
60
10
10
0
0
0
0
0
0
60
60
0
0
0
0
% C
% Asp:
10
0
0
0
20
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
40
0
10
10
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
50
0
0
50
0
0
10
10
0
0
% G
% His:
0
10
10
0
0
10
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
20
10
10
% I
% Lys:
0
10
20
0
20
0
30
0
0
0
0
0
10
0
20
% K
% Leu:
0
10
40
10
0
10
0
0
10
0
0
0
10
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
40
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% N
% Pro:
0
0
0
50
0
10
10
0
20
0
0
60
0
50
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
0
0
0
20
10
20
0
0
0
0
10
0
10
20
% S
% Thr:
0
10
10
20
20
0
10
0
0
10
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
10
20
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
20
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _