KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD11B1
All Species:
34.55
Human Site:
S196
Identified Species:
63.33
UniProt:
P28845
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28845
NP_005516.1
292
32401
S196
A
L
D
G
F
F
S
S
I
R
K
E
Y
S
V
Chimpanzee
Pan troglodytes
XP_001168226
292
32354
S196
A
L
D
G
F
F
S
S
I
R
K
E
Y
S
V
Rhesus Macaque
Macaca mulatta
XP_001110531
292
32393
S196
A
L
D
G
F
F
S
S
I
R
K
E
Y
S
V
Dog
Lupus familis
XP_542145
223
23905
S141
L
L
Q
V
N
L
L
S
Y
V
Q
L
T
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P50172
292
32345
T196
A
L
D
G
F
F
S
T
I
R
T
E
L
Y
I
Rat
Rattus norvegicus
P16232
288
31865
T192
A
L
D
G
F
F
S
T
I
R
K
E
H
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510050
476
52232
S195
A
L
D
G
F
F
S
S
L
R
E
E
F
I
L
Chicken
Gallus gallus
Q6PUF4
287
31460
S196
A
L
D
G
F
F
S
S
L
R
H
E
L
T
M
Frog
Xenopus laevis
Q6P7J1
291
31734
S196
A
L
E
G
F
Y
S
S
L
R
R
E
F
A
L
Zebra Danio
Brachydanio rerio
Q6PUF3
287
31899
G195
A
L
N
G
F
F
G
G
L
Q
N
E
L
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
S219
A
M
Q
A
F
A
D
S
L
R
A
E
V
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197619
254
28550
Y172
F
G
S
L
R
H
D
Y
H
F
Q
Q
M
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
L186
T
D
S
L
R
K
E
L
I
N
T
K
I
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.8
35.6
N.A.
78.4
75.6
N.A.
38.6
42.4
45.2
43.1
N.A.
24.8
N.A.
N.A.
38.3
Protein Similarity:
100
100
97.9
48.2
N.A.
87.6
87.3
N.A.
51
60.2
69.1
61.2
N.A.
43.5
N.A.
N.A.
54.1
P-Site Identity:
100
100
100
20
N.A.
66.6
73.3
N.A.
66.6
66.6
53.3
40
N.A.
33.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
80
93.3
N.A.
93.3
86.6
100
73.3
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
8
0
8
0
0
0
0
8
0
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
54
0
0
0
16
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
8
77
0
0
0
% E
% Phe:
8
0
0
0
77
62
0
0
0
8
0
0
16
0
0
% F
% Gly:
0
8
0
70
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
47
0
0
0
8
8
16
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
31
8
0
0
0
% K
% Leu:
8
77
0
16
0
8
8
8
39
0
0
8
24
8
24
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
24
% M
% Asn:
0
0
8
0
8
0
0
0
0
8
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
8
16
8
0
0
0
% Q
% Arg:
0
0
0
0
16
0
0
0
0
70
8
0
0
8
0
% R
% Ser:
0
0
16
0
0
0
62
62
0
0
0
0
0
31
0
% S
% Thr:
8
0
0
0
0
0
0
16
0
0
16
0
8
8
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
8
0
0
0
24
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _