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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJB2 All Species: 36.06
Human Site: S183 Identified Species: 88.15
UniProt: P29033 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29033 NP_003995.2 226 26215 S183 N T V D C F V S R P T E K T V
Chimpanzee Pan troglodytes XP_001145895 209 24152 R167 T V D C F V S R P T E K T V F
Rhesus Macaque Macaca mulatta Q8MIT8 226 26206 S183 N T V D C F V S R P T E K T V
Dog Lupus familis XP_543177 226 26241 S183 N T V D C F V S R P T E K T V
Cat Felis silvestris
Mouse Mus musculus Q00977 226 26393 S183 N T V D C F I S R P T E K T V
Rat Rattus norvegicus P21994 226 26433 S183 N T V D C F I S R P T E K T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516368 226 26252 S183 N T V D C F V S R P T E K T V
Chicken Gallus gallus O93533 263 30905 S183 N T V D C F V S R P T E K T V
Frog Xenopus laevis P08983 264 29977 S182 N T V D C F V S R P T E K T I
Zebra Danio Brachydanio rerio NP_997990 267 30305 S185 N K V D C F I S R P T E K T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 98.2 98.6 N.A. 92.9 93.8 N.A. 93.8 71.8 56 58.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 99.5 99.1 N.A. 98.2 98.2 N.A. 96.9 79 71.9 68.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 100 100 93.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 90 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 90 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 90 0 0 0 % E
% Phe: 0 0 0 0 10 90 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 30 0 0 0 0 0 0 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 10 90 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 90 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 90 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 10 90 0 0 0 0 0 0 0 % S
% Thr: 10 80 0 0 0 0 0 0 0 10 90 0 10 90 0 % T
% Val: 0 10 90 0 0 10 60 0 0 0 0 0 0 10 80 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _