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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJB2
All Species:
22.42
Human Site:
T123
Identified Species:
54.81
UniProt:
P29033
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29033
NP_003995.2
226
26215
T123
K
D
I
E
E
I
K
T
Q
K
V
R
I
E
G
Chimpanzee
Pan troglodytes
XP_001145895
209
24152
I107
H
E
K
K
R
K
F
I
K
G
E
I
K
S
S
Rhesus Macaque
Macaca mulatta
Q8MIT8
226
26206
T123
K
D
I
E
E
I
K
T
Q
K
V
R
I
E
G
Dog
Lupus familis
XP_543177
226
26241
S123
K
D
I
E
E
I
K
S
Q
K
V
R
I
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q00977
226
26393
T123
K
D
I
E
E
I
K
T
Q
K
V
R
I
E
G
Rat
Rattus norvegicus
P21994
226
26433
T123
K
D
I
E
E
I
K
T
Q
K
V
R
I
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516368
226
26252
R123
K
D
I
E
E
I
K
R
Q
K
V
R
I
E
G
Chicken
Gallus gallus
O93533
263
30905
T123
K
D
I
E
E
I
R
T
Q
R
F
R
I
E
G
Frog
Xenopus laevis
P08983
264
29977
K122
Q
E
L
A
E
V
K
K
H
K
V
K
I
S
G
Zebra Danio
Brachydanio rerio
NP_997990
267
30305
N125
D
D
L
E
S
L
K
N
R
R
L
P
I
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
98.2
98.6
N.A.
92.9
93.8
N.A.
93.8
71.8
56
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.4
99.5
99.1
N.A.
98.2
98.2
N.A.
96.9
79
71.9
68.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
93.3
80
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
93.3
93.3
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
80
80
0
0
0
0
0
10
0
0
70
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
90
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
70
0
10
0
0
0
10
90
0
0
% I
% Lys:
70
0
10
10
0
10
80
10
10
70
0
10
10
0
0
% K
% Leu:
0
0
20
0
0
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
10
10
10
20
0
70
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
10
0
0
0
0
0
20
10
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
70
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _