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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2E1 All Species: 26.67
Human Site: S404 Identified Species: 53.33
UniProt: P29083 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29083 NP_005504.2 439 49452 S404 M V A G R P F S Y S E V S Q R
Chimpanzee Pan troglodytes XP_001165043 439 49464 S404 M V A G R P F S Y S E V S Q R
Rhesus Macaque Macaca mulatta XP_001111102 439 49497 S404 M V A G R P F S Y S E V S Q R
Dog Lupus familis XP_545124 438 49371 S403 M V A G R P F S Y S E V S Q R
Cat Felis silvestris
Mouse Mus musculus Q9D0D5 440 49575 S405 M V A G C P F S Y S E V S Q R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509961 297 33458 P268 P L L L G S G P P S S L R D R
Chicken Gallus gallus XP_416551 441 49929 S406 T V A G R P H S Y S Q V S Q R
Frog Xenopus laevis NP_001080455 433 49015 L398 T V A G R S Y L Y S Q V S Q R
Zebra Danio Brachydanio rerio NP_001038610 447 50244 S412 M V G G R P F S Y R E V S Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524026 429 48267 P394 T V L V A G R P H P L D Q L D
Honey Bee Apis mellifera XP_395253 419 47339 T384 T V T V A G K T V A I A D V N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790549 436 49593 P401 I V M V Q G R P V P L D E V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 96.1 N.A. 92.7 N.A. N.A. 55.3 81.1 76 71.8 N.A. 44.1 43.5 N.A. 40.7
Protein Similarity: 100 99.5 98.4 97.2 N.A. 95 N.A. N.A. 59.6 89.1 85.8 83 N.A. 63 62.4 N.A. 61
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 13.3 80 66.6 86.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 26.6 86.6 80 86.6 N.A. 13.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 59 0 17 0 0 0 0 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 9 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 50 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 67 9 25 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 17 9 0 0 0 9 0 0 17 9 0 9 0 % L
% Met: 50 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 9 0 0 0 0 59 0 25 9 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 17 0 9 67 0 % Q
% Arg: 0 0 0 0 59 0 17 0 0 9 0 0 9 0 75 % R
% Ser: 0 0 0 0 0 17 0 59 0 67 9 0 67 0 0 % S
% Thr: 34 0 9 0 0 0 0 9 0 0 0 0 0 0 9 % T
% Val: 0 92 0 25 0 0 0 0 17 0 0 67 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _