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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2E1 All Species: 40.3
Human Site: T116 Identified Species: 80.61
UniProt: P29083 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29083 NP_005504.2 439 49452 T116 H M R R R I E T D E R D S T N
Chimpanzee Pan troglodytes XP_001165043 439 49464 T116 H M R R R I E T D E R D S T N
Rhesus Macaque Macaca mulatta XP_001111102 439 49497 T116 H M R R R I E T D E R D S T N
Dog Lupus familis XP_545124 438 49371 T116 H M R R R I E T D E R D S T N
Cat Felis silvestris
Mouse Mus musculus Q9D0D5 440 49575 T116 H M R R R I E T D E R N S T N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509961 297 33458 A31 G F Y G L E H A L A L D I L I
Chicken Gallus gallus XP_416551 441 49929 T116 H M R R R I E T D E R D S T N
Frog Xenopus laevis NP_001080455 433 49015 T116 H M R R R I E T D E R D S T N
Zebra Danio Brachydanio rerio NP_001038610 447 50244 T116 H M R R R I E T D E R D S T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524026 429 48267 T130 L M R K R M E T E E R D A T S
Honey Bee Apis mellifera XP_395253 419 47339 T117 L M R K R M E T E E R D A T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790549 436 49593 N120 R M R Q K I E N R E R D S T C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 96.1 N.A. 92.7 N.A. N.A. 55.3 81.1 76 71.8 N.A. 44.1 43.5 N.A. 40.7
Protein Similarity: 100 99.5 98.4 97.2 N.A. 95 N.A. N.A. 59.6 89.1 85.8 83 N.A. 63 62.4 N.A. 61
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 6.6 100 100 100 N.A. 60 60 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 100 100 N.A. 93.3 93.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 9 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 67 0 0 92 0 0 0 % D
% Glu: 0 0 0 0 0 9 92 0 17 92 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 67 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 75 0 0 0 0 0 0 9 0 9 % I
% Lys: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 0 9 0 0 0 9 0 9 0 0 9 0 % L
% Met: 0 92 0 0 0 17 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 67 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 92 67 84 0 0 0 9 0 92 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 75 0 17 % S
% Thr: 0 0 0 0 0 0 0 84 0 0 0 0 0 92 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _