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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2E1
All Species:
18.18
Human Site:
Y246
Identified Species:
36.36
UniProt:
P29083
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29083
NP_005504.2
439
49452
Y246
W
A
T
K
G
P
S
Y
E
D
L
Y
T
Q
N
Chimpanzee
Pan troglodytes
XP_001165043
439
49464
Y246
W
A
T
K
G
P
S
Y
E
D
L
Y
T
Q
N
Rhesus Macaque
Macaca mulatta
XP_001111102
439
49497
Y246
W
A
T
K
G
P
S
Y
E
D
L
Y
T
Q
N
Dog
Lupus familis
XP_545124
438
49371
Y246
W
A
T
K
G
P
S
Y
E
D
L
Y
T
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0D5
440
49575
Y246
W
T
N
K
G
P
S
Y
E
D
L
Y
T
Q
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509961
297
33458
V161
C
T
F
C
E
T
E
V
E
E
D
E
S
A
M
Chicken
Gallus gallus
XP_416551
441
49929
S246
A
W
T
T
K
G
P
S
Y
E
D
L
Y
T
Q
Frog
Xenopus laevis
NP_001080455
433
49015
L246
K
G
P
S
Y
E
D
L
Y
T
Q
D
V
V
I
Zebra Danio
Brachydanio rerio
NP_001038610
447
50244
L246
K
K
G
T
S
Y
D
L
Y
T
Q
N
V
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524026
429
48267
R260
G
F
A
V
E
E
T
R
V
D
V
T
I
G
G
Honey Bee
Apis mellifera
XP_395253
419
47339
D247
S
S
G
F
M
V
E
D
T
R
V
D
V
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790549
436
49593
Q250
G
P
A
E
L
Y
H
Q
D
V
T
I
N
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.4
96.1
N.A.
92.7
N.A.
N.A.
55.3
81.1
76
71.8
N.A.
44.1
43.5
N.A.
40.7
Protein Similarity:
100
99.5
98.4
97.2
N.A.
95
N.A.
N.A.
59.6
89.1
85.8
83
N.A.
63
62.4
N.A.
61
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
6.6
6.6
0
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
20
13.3
0
0
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
34
17
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
9
9
50
17
17
0
0
0
% D
% Glu:
0
0
0
9
17
17
17
0
50
17
0
9
0
0
0
% E
% Phe:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
9
17
0
42
9
0
0
0
0
0
0
0
9
17
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
25
% I
% Lys:
17
9
0
42
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
17
0
0
42
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
42
% N
% Pro:
0
9
9
0
0
42
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
17
0
0
42
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
0
42
9
0
0
0
0
9
0
0
% S
% Thr:
0
17
42
17
0
9
9
0
9
17
9
9
42
17
0
% T
% Val:
0
0
0
9
0
9
0
9
9
9
17
0
25
17
0
% V
% Trp:
42
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
17
0
42
25
0
0
42
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _