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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2E2
All Species:
26.06
Human Site:
S248
Identified Species:
52.12
UniProt:
P29084
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29084
NP_002086.1
291
33044
S248
G
I
S
S
M
Q
E
S
G
P
K
K
V
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083643
291
32996
S248
G
I
S
S
M
Q
E
S
G
P
K
R
V
A
P
Dog
Lupus familis
XP_532814
412
47133
S369
G
I
S
S
M
Q
E
S
G
P
K
K
V
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D902
292
33028
S249
G
I
S
S
M
Q
E
S
G
P
K
K
V
A
S
Rat
Rattus norvegicus
NP_001100788
291
32941
S248
G
I
S
S
M
Q
E
S
G
P
K
K
V
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233400
290
32977
A247
G
I
S
S
M
R
E
A
G
P
R
K
I
A
P
Frog
Xenopus laevis
P29540
288
32606
S245
G
I
S
S
M
Q
E
S
G
P
K
K
I
I
P
Zebra Danio
Brachydanio rerio
NP_997896
291
33019
T247
G
I
S
S
M
Q
E
T
G
P
K
K
M
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523923
292
33372
H244
G
I
R
S
M
Q
D
H
G
L
K
K
A
I
P
Honey Bee
Apis mellifera
XP_001120176
280
32671
Q232
I
D
E
Y
L
E
K
Q
G
I
R
S
M
Q
D
Nematode Worm
Caenorhab. elegans
NP_496466
289
32991
D219
F
T
F
P
E
L
E
D
D
F
K
A
L
W
R
Sea Urchin
Strong. purpuratus
XP_001177241
286
32872
Q238
I
Q
E
Y
L
K
K
Q
G
I
N
S
M
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
67.4
N.A.
94.1
94.1
N.A.
N.A.
81.4
82.4
78.3
N.A.
55.8
60.1
36
52.9
Protein Similarity:
100
N.A.
99.6
68.9
N.A.
96.9
96.9
N.A.
N.A.
92
92.7
90.3
N.A.
73.2
75.2
60.4
74.5
P-Site Identity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
86.6
80
N.A.
60
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
93.3
93.3
N.A.
66.6
40
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
9
9
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
9
9
0
0
0
0
0
17
% D
% Glu:
0
0
17
0
9
9
75
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
75
0
0
0
0
0
0
0
92
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
17
75
0
0
0
0
0
0
0
17
0
0
17
17
0
% I
% Lys:
0
0
0
0
0
9
17
0
0
0
75
67
0
0
0
% K
% Leu:
0
0
0
0
17
9
0
0
0
9
0
0
9
0
0
% L
% Met:
0
0
0
0
75
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
67
0
0
0
0
59
% P
% Gln:
0
9
0
0
0
67
0
17
0
0
0
0
0
17
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
0
17
9
0
0
9
% R
% Ser:
0
0
67
75
0
0
0
50
0
0
0
17
0
0
17
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
42
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _