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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2E2
All Species:
30
Human Site:
S264
Identified Species:
60
UniProt:
P29084
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29084
NP_002086.1
291
33044
S264
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083643
291
32996
S264
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Dog
Lupus familis
XP_532814
412
47133
S385
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D902
292
33028
S265
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Rat
Rattus norvegicus
NP_001100788
291
32941
S264
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233400
290
32977
S262
A
Q
R
K
K
P
T
S
Q
K
K
R
R
F
K
Frog
Xenopus laevis
P29540
288
32606
T260
V
Q
K
R
K
K
A
T
S
Q
R
R
R
F
K
Zebra Danio
Brachydanio rerio
NP_997896
291
33019
T263
Q
K
R
K
K
P
G
T
Q
R
K
R
R
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523923
292
33372
K259
K
R
K
K
A
A
N
K
K
R
Q
F
K
K
P
Honey Bee
Apis mellifera
XP_001120176
280
32671
I254
P
I
K
R
K
K
P
I
S
K
R
K
Q
F
K
Nematode Worm
Caenorhab. elegans
NP_496466
289
32991
L242
E
K
K
I
E
E
Y
L
Q
K
K
G
L
D
A
Sea Urchin
Strong. purpuratus
XP_001177241
286
32872
P254
G
P
K
K
F
N
A
P
Q
R
K
K
P
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
67.4
N.A.
94.1
94.1
N.A.
N.A.
81.4
82.4
78.3
N.A.
55.8
60.1
36
52.9
Protein Similarity:
100
N.A.
99.6
68.9
N.A.
96.9
96.9
N.A.
N.A.
92
92.7
90.3
N.A.
73.2
75.2
60.4
74.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
80
40
66.6
N.A.
13.3
26.6
20
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
53.3
60
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
9
59
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
9
0
67
0
% F
% Gly:
9
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
17
42
75
75
17
0
9
9
67
75
17
9
9
75
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
0
% N
% Pro:
9
9
0
0
0
59
9
9
0
0
0
0
9
0
9
% P
% Gln:
50
17
0
0
0
0
0
0
75
9
9
0
9
0
0
% Q
% Arg:
0
50
59
17
0
0
0
0
0
25
17
67
67
0
9
% R
% Ser:
0
0
0
0
0
0
0
50
17
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _