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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2E2 All Species: 4.55
Human Site: T41 Identified Species: 9.09
UniProt: P29084 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29084 NP_002086.1 291 33044 T41 S S S K K K K T K V E H G G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001083643 291 32996 T41 S S S K K K K T K V E H G G S
Dog Lupus familis XP_532814 412 47133 A162 S S S K K K K A K L E H G G S
Cat Felis silvestris
Mouse Mus musculus Q9D902 292 33028 A42 S S S K K K K A K V E H G G S
Rat Rattus norvegicus NP_001100788 291 32941 A41 S S S K K K K A K V E H G G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233400 290 32977 K41 S S K K K K V K V E Q G G P S
Frog Xenopus laevis P29540 288 32606 E41 K K K R A K L E L S S T S G S
Zebra Danio Brachydanio rerio NP_997896 291 33019 K41 S S K K K K S K P D K E S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523923 292 33372 R41 P P P S D D S R R K M R P P N
Honey Bee Apis mellifera XP_001120176 280 32671 K41 R D E P F K K K P K P S S V S
Nematode Worm Caenorhab. elegans NP_496466 289 32991 A43 Y S S E A A K A K K K K S S G
Sea Urchin Strong. purpuratus XP_001177241 286 32872 K41 E P P P K K K K P G S G F S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.9 67.4 N.A. 94.1 94.1 N.A. N.A. 81.4 82.4 78.3 N.A. 55.8 60.1 36 52.9
Protein Similarity: 100 N.A. 99.6 68.9 N.A. 96.9 96.9 N.A. N.A. 92 92.7 90.3 N.A. 73.2 75.2 60.4 74.5
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. N.A. 46.6 20 40 N.A. 0 20 26.6 20
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 53.3 26.6 46.6 N.A. 13.3 20 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 9 0 34 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 9 9 0 0 0 9 0 0 0 0 0 % D
% Glu: 9 0 9 9 0 0 0 9 0 9 42 9 0 0 9 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 17 50 50 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 25 59 67 84 67 34 50 25 17 9 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 9 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 9 17 17 17 0 0 0 0 25 0 9 0 9 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 9 0 0 9 0 0 0 9 9 0 0 9 0 0 0 % R
% Ser: 59 67 50 9 0 0 17 0 0 9 17 9 34 25 75 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 9 0 9 34 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _