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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK1
All Species:
0
Human Site:
S108
Identified Species:
0
UniProt:
P29120
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29120
NP_000430.3
753
84152
S108
Q
Q
Y
E
K
E
R
S
K
R
S
A
L
R
D
Chimpanzee
Pan troglodytes
XP_517645
753
84134
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
Dog
Lupus familis
XP_848637
753
84126
Cat
Felis silvestris
Mouse
Mus musculus
P63239
753
84155
Rat
Rattus norvegicus
P28840
752
84102
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512273
758
84714
Chicken
Gallus gallus
Frog
Xenopus laevis
P29119
783
86425
Zebra Danio
Brachydanio rerio
NP_001131134
755
84185
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30430
1101
120975
Honey Bee
Apis mellifera
XP_393918
714
80231
Nematode Worm
Caenorhab. elegans
P51559
943
103128
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
42.9
96.4
N.A.
92.5
92.6
N.A.
78.2
N.A.
41.2
72.5
N.A.
32.6
44
33.8
N.A.
Protein Similarity:
100
100
58.5
97.8
N.A.
96.4
96.1
N.A.
84.4
N.A.
57.4
84.1
N.A.
45.7
58.7
49.4
N.A.
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
N.A.
0
0
N.A.
0
0
0
N.A.
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
N.A.
0
0
N.A.
0
0
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
0
100
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
100
0
0
0
100
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
100
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
100
0
0
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _