KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK1
All Species:
12.42
Human Site:
S679
Identified Species:
22.78
UniProt:
P29120
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29120
NP_000430.3
753
84152
S679
Q
S
A
F
S
K
N
S
P
P
K
Q
S
P
K
Chimpanzee
Pan troglodytes
XP_517645
753
84134
S679
Q
S
A
F
S
K
N
S
P
P
K
Q
S
P
K
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
S679
E
Q
T
C
S
R
Q
S
Q
S
S
R
E
S
P
Dog
Lupus familis
XP_848637
753
84126
S679
Q
S
A
F
S
K
N
S
P
P
K
Q
S
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P63239
753
84155
A679
Q
S
A
F
S
K
N
A
L
S
K
Q
S
P
K
Rat
Rattus norvegicus
P28840
752
84102
N678
L
Q
S
A
F
S
K
N
T
P
S
K
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512273
758
84714
M684
Q
N
A
L
N
K
Q
M
V
P
N
R
A
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
P29119
783
86425
T652
S
C
A
T
C
K
G
T
T
I
N
D
C
L
T
Zebra Danio
Brachydanio rerio
NP_001131134
755
84185
N683
R
L
L
Q
S
A
F
N
R
Q
M
P
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30430
1101
120975
V939
R
S
S
L
T
Q
L
V
E
V
P
S
R
V
C
Honey Bee
Apis mellifera
XP_393918
714
80231
N644
A
I
G
P
K
E
N
N
G
T
I
E
G
F
A
Nematode Worm
Caenorhab. elegans
P51559
943
103128
W852
P
E
G
S
T
K
S
W
Q
C
E
D
C
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
S701
Y
F
M
F
F
M
K
S
R
R
R
I
R
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
42.9
96.4
N.A.
92.5
92.6
N.A.
78.2
N.A.
41.2
72.5
N.A.
32.6
44
33.8
N.A.
Protein Similarity:
100
100
58.5
97.8
N.A.
96.4
96.1
N.A.
84.4
N.A.
57.4
84.1
N.A.
45.7
58.7
49.4
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
80
6.6
N.A.
40
N.A.
13.3
6.6
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
26.6
N.A.
66.6
N.A.
20
26.6
N.A.
33.3
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
47
8
0
8
0
8
0
0
0
0
16
8
8
% A
% Cys:
0
8
0
8
8
0
0
0
0
8
0
0
16
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
8
0
8
8
8
0
0
% E
% Phe:
0
8
0
39
16
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
16
0
0
0
8
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
0
0
0
0
8
54
16
0
0
0
31
8
0
0
47
% K
% Leu:
8
8
8
16
0
0
8
0
8
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
8
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
39
24
0
0
16
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
24
39
8
8
0
39
16
% P
% Gln:
39
16
0
8
0
8
16
0
16
8
0
31
8
0
0
% Q
% Arg:
16
0
0
0
0
8
0
0
16
8
8
16
16
8
0
% R
% Ser:
8
39
16
8
47
8
8
39
0
16
16
8
31
24
16
% S
% Thr:
0
0
8
8
16
0
0
8
16
8
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _