KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK1
All Species:
22.73
Human Site:
T568
Identified Species:
41.67
UniProt:
P29120
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29120
NP_000430.3
753
84152
T568
E
N
P
I
G
T
W
T
L
R
I
T
D
M
S
Chimpanzee
Pan troglodytes
XP_517645
753
84134
T568
E
N
P
I
G
T
W
T
L
R
I
T
D
M
S
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
V548
E
D
P
S
G
E
W
V
L
E
I
E
N
T
S
Dog
Lupus familis
XP_848637
753
84126
T568
E
N
P
I
G
T
W
T
L
R
I
T
D
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P63239
753
84155
T568
E
N
P
V
G
T
W
T
L
K
I
T
D
M
S
Rat
Rattus norvegicus
P28840
752
84102
T568
E
N
P
V
G
T
W
T
L
K
V
T
D
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512273
758
84714
T574
E
N
P
V
G
T
W
T
L
R
I
T
D
M
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P29119
783
86425
V546
E
D
P
A
G
E
W
V
L
E
I
E
N
V
S
Zebra Danio
Brachydanio rerio
NP_001131134
755
84185
I571
E
N
P
T
G
T
W
I
L
K
I
T
D
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30430
1101
120975
Q765
E
S
P
Q
G
N
W
Q
L
E
I
H
N
E
G
Honey Bee
Apis mellifera
XP_393918
714
80231
C542
R
F
E
A
E
D
E
C
R
A
A
E
N
E
I
Nematode Worm
Caenorhab. elegans
P51559
943
103128
L600
E
D
P
R
G
T
W
L
L
M
V
E
S
V
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
K569
E
N
G
V
G
D
W
K
I
K
V
K
T
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
42.9
96.4
N.A.
92.5
92.6
N.A.
78.2
N.A.
41.2
72.5
N.A.
32.6
44
33.8
N.A.
Protein Similarity:
100
100
58.5
97.8
N.A.
96.4
96.1
N.A.
84.4
N.A.
57.4
84.1
N.A.
45.7
58.7
49.4
N.A.
P-Site Identity:
100
100
46.6
93.3
N.A.
86.6
80
N.A.
93.3
N.A.
46.6
73.3
N.A.
40
0
40
N.A.
P-Site Similarity:
100
100
60
100
N.A.
100
100
N.A.
100
N.A.
66.6
80
N.A.
53.3
6.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
0
16
0
0
0
0
0
0
54
0
0
% D
% Glu:
93
0
8
0
8
16
8
0
0
24
0
31
0
16
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
93
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
24
0
0
0
8
8
0
70
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
31
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
85
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
39
0
% M
% Asn:
0
62
0
0
0
8
0
0
0
0
0
0
31
0
0
% N
% Pro:
0
0
85
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
8
31
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
70
% S
% Thr:
0
0
0
8
0
62
0
47
0
0
0
54
8
24
8
% T
% Val:
0
0
0
31
0
0
0
16
0
0
24
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
93
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _